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European Journal of Neurology|August 12, 2018
Prevalence and phenotype of the c.1529C>T SPG7 variant in adult-onset cerebellar ataxia in ItalyC Mancini, E Giorgio, A Rubegni, et al.Science (New York, N.Y.)|March 8, 1996
Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansionV Campuzano, L Montermini, M D Moltò, et al.The Journal of Pharmacology and Experimental Therapeutics|May 13, 2006
Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivoBrianne Weiss, Andrew Alt, Ann Marie Ogden, et al.Journal of Medicinal Chemistry|September 20, 2002
Ethyl (3S,4aR,6S,8aR)-6-(4-ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso-quinoline-3-carboxylic ester: a prodrug of a GluR5 kainate receptor antagonist active in two animal models of acute migraineSandra A Filla, Mark A Winter, Kirk W Johnson, et al.Bioorganic & Medicinal Chemistry Letters|October 15, 2013
GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain modelsJose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.Neurology|August 8, 2008
Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptomsT Schmitz-Hübsch, M Coudert, P Bauer, et al.Bioorganic & Medicinal Chemistry Letters|October 22, 2013
GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacyJose A Martinez-Perez, Smriti Iyengar, Harlan E Shannon, et al.Journal of Medicinal Chemistry|June 25, 2005
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of painEsteban Dominguez, Smriti Iyengar, Harlan E Shannon, et al.Neurology|August 12, 2011
The natural history of spinocerebellar ataxia type 1, 2, 3, and 6: a 2-year follow-up studyH Jacobi, P Bauer, P Giunti, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a potent, dual serotonin and norepinephrine reuptake inhibitorNicolas Dreyfus, Jason K Myers, Valentina O Badescu, et al.Pageof 13