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Plos Pathogens|November 19, 2010
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4Edel A McNeela, Aine Burke, Daniel R Neill, et al.
Nature Communications|June 15, 2019
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodiesTae-Eun Park, Nur Mustafaoglu, Anna Herland, et al.
Immunity|February 21, 2012
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosisKenichi Shimada, Timothy R Crother, Justin Karlin, et al.
Journal of Immunology (Baltimore, Md. : 1950)|October 28, 2025
Fibroblast activation protein promotes natural killer cell invasion and tumor infiltrationRachael E Maynard, Allison A Fitzgerald, Emily F Marcisak, et al.
Science (New York, N.Y.)|October 27, 2018
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell deathPontus Orning, Dan Weng, Kristian Starheim, et al.
Biorxiv : the Preprint Server for Biology|October 4, 2023
Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancerLoretah Chibaya, Christina F Lusi, Kelly D DeMarco, et al.
Cell Reports. Medicine|October 10, 2025
Super-adjuvant nanoparticles for platform cancer vaccinationGriffin I Kane, Tiana E Naylor, Ellis F Lusi, et al.
Journal of Medicinal Chemistry|March 23, 2026
Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING PathwayLeonard Barasa, Leo DeOrsey, Maeve D O'Reilly, et al.
SLAS Discovery : Advancing Life Sciences R & D|September 15, 2023
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensorsEdward A FitzGerald, Darius Vagrys, Giulia Opassi, et al.
Cell Metabolism|May 29, 2018
A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast CancerJeremy C Borniger, William H Walker Ii, Surbhi, et al.
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