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Cancer Research|September 1, 1990
Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivoA L Jackman, G A Taylor, B M O'Connor, et al.
Melanoma Research|April 4, 2002
Effect of temozolomide on central nervous system relapse in patients with advanced melanomaM J Paul, Y Summers, A H Calvert, et al.
British Journal of Cancer|February 1, 1991
Phase II trial of trimelamol in refractory ovarian cancerI R Judson, A H Calvert, M E Gore, et al.
Biochimie|January 1, 1995
The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapyR J Griffin, N J Curtin, D R Newell, et al.
British Journal of Cancer|October 1, 1994
A Cancer Research Campaign (CRC) phase II trial of CB10-277 given by 24 hour infusion for malignant melanomaN M Bleehen, A H Calvert, S M Lee, et al.
Advances in Enzyme Regulation|January 1, 1989
Thymidylate synthase: a target for anticancer drug designK R Harrap, A L Jackman, D R Newell, et al.
Cancer Investigation|March 20, 2003
Cancer drug development in Europe: a selection of new agents under development at the European Drug Development NetworkD Lacombe, A Butler-Smith, P Therasse, et al.
Annals of Oncology : Official Journal of the European Society for Medical Oncology|June 4, 1999
Pharmacokinetically guided dose escalation of carboplatin in epithelial ovarian cancer: effect on drug-plasma AUC and peripheral blood drug-DNA adduct levelsS Ghazal-Aswad, M J Tilby, M Lind, et al.
Journal of Medicinal Chemistry|March 1, 1991
Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analoguesT J Thornton, T R Jones, A L Jackman, et al.
Journal of Medicinal Chemistry|September 30, 1994
The synthesis and thymidylate synthase inhibitory activity of L-gamma-L-linked dipeptide and L-gamma-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)G M Bisset, V Bavetsias, T J Thornton, et al.
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