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Gene Therapy|January 23, 2009
Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancerK Birkholz, A Hombach, C Krug, et al.Gut|February 13, 2004
An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivoA Stallmach, T Marth, B Weiss, et al.International Journal of Cancer|July 9, 1993
CD30-antigen-specific targeting and activation of T cells via murine bispecific monoclonal antibodies against CD3 and CD28: potential use for the treatment of Hodgkin's lymphomaC Pohl, R Denfeld, C Renner, et al.Clinical Immunology (Orlando, Fla.)|April 13, 2011
Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formationGunter Rappl, Stefan Pabst, Dagmar Riemann, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 18, 2011
CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activationDavid M Kofler, Markus Chmielewski, Gunter Rappl, et al.Frontiers in Immunology|February 23, 2023
CAR and TCR form individual signaling synapses and do not cross-activate, however, can co-operate in T cell activationMarkus Barden, Astrid Holzinger, Lukas Velas, et al.International Journal of Cancer|August 30, 2000
An entirely humanized CD3 zeta-chain signaling receptor that directs peripheral blood t cells to specific lysis of carcinoembryonic antigen-positive tumor cellsA Hombach, C Schneider, D Sent, et al.Der Pathologe|August 24, 2010
[Adoptive T-cell therapy of rhabdomyosarcoma]K Simon-Keller, A Paschen, S Eichmüller, et al.Cancer Research|February 25, 2010
The proteasome inhibitor bortezomib sensitizes melanoma cells toward adoptive CTL attackJens Michael Seeger, Patrick Schmidt, Kerstin Brinkmann, et al.Methods in Molecular Biology (Clifton, N.J.)|August 22, 2012
Chimeric antigen receptors for T-cell based therapyEleanor J Cheadle, Vicky Sheard, Andreas A Hombach, et al.Pageof 8