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A J Townsend

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The Journal of Biological Chemistry|May 17, 1996
De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethalityK D Bunting, A J Townsend
The Journal of Biological Chemistry|May 17, 1996
Protection by transfected rat or human class 3 aldehyde dehydrogenase against the cytotoxic effects of oxazaphosphorine alkylating agents in hamster V79 cell lines. Demonstration of aldophosphamide metabolism by the human cytosolic class 3 isozymeK D Bunting, A J Townsend
Biochemical Pharmacology|August 11, 1998
Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acroleinK D Bunting, A J Townsend
Molecular Pharmacology|September 1, 1987
Sequence-specific effects of ara-5-aza-CTP and ara-CTP on DNA synthesis by purified human DNA polymerases in vitro: visualization of chain elongation on a defined templateA J Townsend, Y C Cheng
Acta Tropica|December 1, 1979
A trypanosomiasis survey of wild animals in the Luangwa Valley, ZambiaJ S Dillmann, A J Townsend
Carcinogenesis|June 1, 1994
Protection by transfected glutathione S-transferase isozymes against carcinogen-induced alkylation of cellular macromolecules in human MCF-7 cellsW R Fields, Y Li, A J Townsend
The Journal of Biological Chemistry|September 16, 1994
Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenaseK D Bunting, R Lindahl, A J Townsend
Free Radical Biology & Medicine|April 11, 2001
Apoptosis in RAW 264.7 cells exposed to 4-hydroxy-2-nonenal: dependence on cytochrome C release but not p53 accumulationR L Haynes, B Brune, A J Townsend
Alcoholism, Clinical and Experimental Research|January 1, 1983
Effect of ethanol on alkaline phosphatase activity in HeLa cellsB Goz, A C Stowe, A J Townsend
Molecular Carcinogenesis|December 7, 2000
Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cellsC S Morrow, P K Smitherman, A J Townsend
Pageof 5

Showing results (1-10 of 45) with videos related to

Sort By:
Pageof 5
The Journal of Biological Chemistry|May 17, 1996
De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethalityK D Bunting, A J Townsend
The Journal of Biological Chemistry|May 17, 1996
Protection by transfected rat or human class 3 aldehyde dehydrogenase against the cytotoxic effects of oxazaphosphorine alkylating agents in hamster V79 cell lines. Demonstration of aldophosphamide metabolism by the human cytosolic class 3 isozymeK D Bunting, A J Townsend
Biochemical Pharmacology|August 11, 1998
Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acroleinK D Bunting, A J Townsend
Molecular Pharmacology|September 1, 1987
Sequence-specific effects of ara-5-aza-CTP and ara-CTP on DNA synthesis by purified human DNA polymerases in vitro: visualization of chain elongation on a defined templateA J Townsend, Y C Cheng
Acta Tropica|December 1, 1979
A trypanosomiasis survey of wild animals in the Luangwa Valley, ZambiaJ S Dillmann, A J Townsend
Carcinogenesis|June 1, 1994
Protection by transfected glutathione S-transferase isozymes against carcinogen-induced alkylation of cellular macromolecules in human MCF-7 cellsW R Fields, Y Li, A J Townsend
The Journal of Biological Chemistry|September 16, 1994
Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenaseK D Bunting, R Lindahl, A J Townsend
Free Radical Biology & Medicine|April 11, 2001
Apoptosis in RAW 264.7 cells exposed to 4-hydroxy-2-nonenal: dependence on cytochrome C release but not p53 accumulationR L Haynes, B Brune, A J Townsend
Alcoholism, Clinical and Experimental Research|January 1, 1983
Effect of ethanol on alkaline phosphatase activity in HeLa cellsB Goz, A C Stowe, A J Townsend
Molecular Carcinogenesis|December 7, 2000
Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cellsC S Morrow, P K Smitherman, A J Townsend
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