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Biochemical Pharmacology|November 1, 1988
Formation and retention and biological activity of N10-propargyl-5,8-dideazafolic acid (CB3717) polyglutamates in L1210 cells in vitroE Sikora, A L Jackman, D R Newell, et al.
Advances in Experimental Medicine and Biology|January 1, 1991
ICI D1694, an inhibitor of thymidylate synthase for clinical studyA L Jackman, D I Jodrell, W Gibson, et al.
Japanese Journal of Cancer Research : Gann|November 1, 1995
Effect of hammerhead ribozyme against human thymidylate synthase on the cytotoxicity of thymidylate synthase inhibitorsH Kobayashi, Y Takemura, H Miyachi, et al.
Cancer Research|June 1, 1986
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studiesA L Jackman, D L Alison, A H Calvert, et al.
Anti-Cancer Drug Design|October 1, 1995
Quinazoline thymidylate synthase inhibitors: methods for assessing the contribution of polyglutamation to their in vitro activityA L Jackman, R Kimbell, M Brown, et al.
The Journal of Biological Chemistry|May 25, 1987
Analysis of thymidylate synthase gene amplification and of mRNA levels in the cell cycleA M Imam, P H Crossley, A L Jackman, et al.
Advances in Experimental Medicine and Biology|January 1, 1993
The role of the reduced-folate carrier and metabolism to intracellular polyglutamates for the activity of ICI D1694A L Jackman, W Gibson, M Brown, et al.
British Journal of Cancer|August 7, 2001
The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibitionS D Webley, S J Welsh, A L Jackman, et al.
Biochemical Pharmacology|October 15, 1984
Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717A L Jackman, G A Taylor, A H Calvert, et al.
Cytometry|September 2, 1998
Cell cycle effects of CB30865, a lipophilic quinazoline-based analogue of the antifolate thymidylate synthase inhibitor ICI 198583 with an undefined mechanism of actionL A Skelton, M G Ormerod, J C Titley, et al.
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