A L Jackman - JoVE Visualize

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European Journal of Cancer (Oxford, England : 1990)|June 1, 1995

Relationships between resistance to cisplatin and antifolates in sensitive and resistant tumour cell linesL R Kelland, R Kimbell, A Hardcastle, et al.

Japanese Journal of Cancer Research : Gann|July 1, 1996

Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugsY Takemura, H Kobayashi, H Miyachi, et al.

Journal of Cancer Research and Clinical Oncology|January 1, 1996

Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drugY Takemura, W Gibson, R Kimbell, et al.

International Journal of Cancer|March 28, 1996

The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cellsY Takemura, H Kobayashi, W Gibson, et al.

British Journal of Cancer|May 1, 1995

Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694S J Freemantle, A L Jackman, L R Kelland, et al.

Journal of Medicinal Chemistry|March 6, 1992

Syntheses and thymidylate synthase inhibitory activity of the poly-gamma-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino ]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolatesG M Bisset, K Pawelczak, A L Jackman, et al.

Anti-Cancer Drug Design|March 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: computer modelling of the N10 substituentT R Jones, R F Betteridge, S Neidle, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 22, 2000

Leucovorin rescue from raltitrexed (tomudex)-induced antiproliferative effects: in vitro cell line and in vivo mouse studiesD C Farrugia, G W Aherne, L Brunton, et al.

British Journal of Cancer|August 23, 2000

Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331S D Webley, A Hardcastle, R D Ladner, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 6, 2000

The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): genetic differences between BALB/c and DBA/2 miceD M Pritchard, L Bower, C S Potten, et al.

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Showing results (21-30 of 86) with videos related to

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European Journal of Cancer (Oxford, England : 1990)|June 1, 1995

Relationships between resistance to cisplatin and antifolates in sensitive and resistant tumour cell linesL R Kelland, R Kimbell, A Hardcastle, et al.

Japanese Journal of Cancer Research : Gann|July 1, 1996

Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugsY Takemura, H Kobayashi, H Miyachi, et al.

Journal of Cancer Research and Clinical Oncology|January 1, 1996

Cellular pharmacokinetics of ZD1694 in cultured human leukaemia cells sensitive, or made resistant, to this drugY Takemura, W Gibson, R Kimbell, et al.

International Journal of Cancer|March 28, 1996

The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cellsY Takemura, H Kobayashi, W Gibson, et al.

British Journal of Cancer|May 1, 1995

Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694S J Freemantle, A L Jackman, L R Kelland, et al.

Journal of Medicinal Chemistry|March 6, 1992

Syntheses and thymidylate synthase inhibitory activity of the poly-gamma-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino ]-2-thenoyl]-L-glutamic acid (ICI D1694) and other quinazoline antifolatesG M Bisset, K Pawelczak, A L Jackman, et al.

Anti-Cancer Drug Design|March 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: computer modelling of the N10 substituentT R Jones, R F Betteridge, S Neidle, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 22, 2000

Leucovorin rescue from raltitrexed (tomudex)-induced antiproliferative effects: in vitro cell line and in vivo mouse studiesD C Farrugia, G W Aherne, L Brunton, et al.

British Journal of Cancer|August 23, 2000

Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331S D Webley, A Hardcastle, R D Ladner, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 6, 2000

The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): genetic differences between BALB/c and DBA/2 miceD M Pritchard, L Bower, C S Potten, et al.

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