A L Jackman - JoVE Visualize

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Proceedings of the National Academy of Sciences of the United States of America|March 4, 1997

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbationD M Pritchard, A J Watson, C S Potten, et al.

Journal of Medicinal Chemistry|January 5, 1996

Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)V Bavetsias, A L Jackman, R Kimbell, et al.

British Journal of Cancer|April 17, 1999

A novel class of lipophilic quinazoline-based folic acid analogues: cytotoxic agents with a folate-independent locusL A Skelton, M G Ormerod, J Titley, et al.

Cancer Research|December 1, 1990

Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitorsG Jansen, J H Schornagel, G R Westerhof, et al.

Cancer Research|March 30, 1999

A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C170HM2C Rohlff, S A Watson, T M Morris, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 29, 2000

Comparison of thymidylate synthase (TS) protein up-regulation after exposure to TS inhibitors in normal and tumor cell lines and tissuesS J Welsh, J Titley, L Brunton, et al.

Bioorganic & Medicinal Chemistry Letters|November 21, 2001

Cyclopenta[g]quinazoline-based antifolates: the effect of the chirality at the 6-position on the inhibition of thymidylate synthase (TS)V Bavetsias, J H Marriott, D S Theti, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 3, 2000

Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicityS J Clarke, D C Farrugia, G W Aherne, et al.

Journal of Medicinal Chemistry|February 2, 1996

Quinazoline antifolates thymidylate synthase inhibitors: lipophilic analogues with modification to the C2-methyl substituentL F Hennequin, F T Boyle, J M Wardleworth, et al.

Cancer Research|March 1, 1992

Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitorB M O'Connor, A L Jackman, P H Crossley, et al.

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Showing results (31-40 of 86) with videos related to

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Proceedings of the National Academy of Sciences of the United States of America|March 4, 1997

Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbationD M Pritchard, A J Watson, C S Potten, et al.

Journal of Medicinal Chemistry|January 5, 1996

Quinazoline antifolate thymidylate synthase inhibitors: gamma-linked L-D, D-D, and D-L dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)V Bavetsias, A L Jackman, R Kimbell, et al.

British Journal of Cancer|April 17, 1999

A novel class of lipophilic quinazoline-based folic acid analogues: cytotoxic agents with a folate-independent locusL A Skelton, M G Ormerod, J Titley, et al.

Cancer Research|December 1, 1990

Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitorsG Jansen, J H Schornagel, G R Westerhof, et al.

Cancer Research|March 30, 1999

A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C170HM2C Rohlff, S A Watson, T M Morris, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 29, 2000

Comparison of thymidylate synthase (TS) protein up-regulation after exposure to TS inhibitors in normal and tumor cell lines and tissuesS J Welsh, J Titley, L Brunton, et al.

Bioorganic & Medicinal Chemistry Letters|November 21, 2001

Cyclopenta[g]quinazoline-based antifolates: the effect of the chirality at the 6-position on the inhibition of thymidylate synthase (TS)V Bavetsias, J H Marriott, D S Theti, et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 3, 2000

Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicityS J Clarke, D C Farrugia, G W Aherne, et al.

Journal of Medicinal Chemistry|February 2, 1996

Quinazoline antifolates thymidylate synthase inhibitors: lipophilic analogues with modification to the C2-methyl substituentL F Hennequin, F T Boyle, J M Wardleworth, et al.

Cancer Research|March 1, 1992

Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitorB M O'Connor, A L Jackman, P H Crossley, et al.

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