A L Jackman - JoVE Visualize

Showing results (41-50 of 86) with videos related to

Pageof 9

Sort By:

Journal of Medicinal Chemistry|January 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: synthesis of four oligo(L-gamma-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid and their enzyme inhibitionK Pawelczak, T R Jones, M Kempny, et al.

Biochemical Pharmacology|February 24, 1993

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitor, ICI D1694, in mouse and human cultured cellsW Gibson, G M Bisset, P R Marsham, et al.

Journal of Medicinal Chemistry|April 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potencyT R Jones, T J Thornton, A Flinn, et al.

Journal of Medicinal Chemistry|August 9, 2002

The design and synthesis of water-soluble analogues of CB30865, a quinazolin-4-one-based antitumor agentV Bavetsias, L A Skelton, F Yafai, et al.

Analytical Biochemistry|August 1, 1988

Development of an assay for the estimation of N10-propargyl-5,8-dideazafolic acid polyglutamates in tumor cellsE Sikora, D R Newell, A L Jackman, et al.

Biochemical Pharmacology|December 14, 1993

The in vivo metabolic stability of dipeptide analogues of the quinazoline antifolate, ICI 198583, in miceD I Jodrell, W Gibson, G M Bisset, et al.

British Journal of Cancer|December 4, 1998

The renal effects of the water-soluble, non-folylpolyglutamate synthetase-dependent thymidylate synthase inhibitor ZD9331 in miceM I Walton, F Mitchell, G W Aherne, et al.

Journal of Medicinal Chemistry|May 23, 2000

Design and synthesis of Cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents(,)V Bavetsias, J H Marriott, C Melin, et al.

Journal of Medicinal Chemistry|June 12, 1992

Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analoguesT J Thornton, A L Jackman, P R Marsham, et al.

Cancer Research|October 15, 1991

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systemsG R Westerhof, G Jansen, N van Emmerik, et al.

Pageof 9

Showing results (41-50 of 86) with videos related to

Sort By:

Pageof 9

Journal of Medicinal Chemistry|January 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: synthesis of four oligo(L-gamma-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid and their enzyme inhibitionK Pawelczak, T R Jones, M Kempny, et al.

Biochemical Pharmacology|February 24, 1993

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitor, ICI D1694, in mouse and human cultured cellsW Gibson, G M Bisset, P R Marsham, et al.

Journal of Medicinal Chemistry|April 1, 1989

Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potencyT R Jones, T J Thornton, A Flinn, et al.

Journal of Medicinal Chemistry|August 9, 2002

The design and synthesis of water-soluble analogues of CB30865, a quinazolin-4-one-based antitumor agentV Bavetsias, L A Skelton, F Yafai, et al.

Analytical Biochemistry|August 1, 1988

Development of an assay for the estimation of N10-propargyl-5,8-dideazafolic acid polyglutamates in tumor cellsE Sikora, D R Newell, A L Jackman, et al.

Biochemical Pharmacology|December 14, 1993

The in vivo metabolic stability of dipeptide analogues of the quinazoline antifolate, ICI 198583, in miceD I Jodrell, W Gibson, G M Bisset, et al.

British Journal of Cancer|December 4, 1998

The renal effects of the water-soluble, non-folylpolyglutamate synthetase-dependent thymidylate synthase inhibitor ZD9331 in miceM I Walton, F Mitchell, G W Aherne, et al.

Journal of Medicinal Chemistry|May 23, 2000

Design and synthesis of Cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents(,)V Bavetsias, J H Marriott, C Melin, et al.

Journal of Medicinal Chemistry|June 12, 1992

Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analoguesT J Thornton, A L Jackman, P R Marsham, et al.

Cancer Research|October 15, 1991

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systemsG R Westerhof, G Jansen, N van Emmerik, et al.

Pageof 9