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Cancer Research|September 1, 1990
Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivoA L Jackman, G A Taylor, B M O'Connor, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 14, 2001
Pharmacokinetic/pharmacodynamic study of ZD9331, a nonpolyglutamatable inhibitor of thymidylate synthase, in a murine model following two curative administration schedulesG W Aherne, A Hardcastle, E Ward, et al.Journal of Medicinal Chemistry|May 9, 1997
Folate-based inhibitors of thymidylate synthase: synthesis and antitumor activity of gamma-linked sterically hindered dipeptide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)V Bavetsias, A L Jackman, J H Marriott, et al.Advances in Enzyme Regulation|January 1, 1989
Thymidylate synthase: a target for anticancer drug designK R Harrap, A L Jackman, D R Newell, et al.Journal of Medicinal Chemistry|March 1, 1991
Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analoguesT J Thornton, T R Jones, A L Jackman, et al.The Journal of Pharmacology and Experimental Therapeutics|May 1, 1996
Preclinical pharmacology of CB30900, a novel dipeptide inhibitor of thymidylate synthase, in miceM I Walton, W Gibson, G W Aherne, et al.Anti-Cancer Drug Design|December 1, 1996
Prodrugs of thymidylate synthase inhibitors: potential for antibody directed enzyme prodrug therapy (ADEPT)C J Springer, V Bavetsias, A L Jackman, et al.Journal of Medicinal Chemistry|September 30, 1994
The synthesis and thymidylate synthase inhibitory activity of L-gamma-L-linked dipeptide and L-gamma-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)G M Bisset, V Bavetsias, T J Thornton, et al.Journal of Medicinal Chemistry|October 3, 1999
Design and synthesis of potent non-polyglutamatable quinazoline antifolate thymidylate synthase inhibitorsP R Marsham, J M Wardleworth, F T Boyle, et al.Advances in Enzyme Regulation|January 1, 1991
Thymidylate synthase inhibitors: the in vitro activity of a series of heterocyclic benzoyl ring modified 2-desamino-2-methyl-N10-substituted-5,8-dideazafolatesA L Jackman, P R Marsham, R G Moran, et al.Pageof 9