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Acta Neuropathologica Communications|August 6, 2024
Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastomaFoteini Tsiami, Chiara Lago, Noemi Pozza, et al.Acta Neuropathologica|March 5, 2019
TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastomaMalte Hellwig, Marlen C Lauffer, Michael Bockmayr, et al.Acta Neuropathologica Communications|December 7, 2019
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migrationMelanie Schoof, Michael Launspach, Dörthe Holdhof, et al.Journal of Experimental & Clinical Cancer Research : CR|March 13, 2024
Functionally-instructed modifiers of response to ATR inhibition in experimental gliomaBianca Walter, Sophie Hirsch, Laurence Kuhlburger, et al.Neuro-Oncology|May 22, 2019
A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastomaEkaterina Pak, Ethan L MacKenzie, Xuesong Zhao, et al.Developmental Neuroscience|January 20, 2021
The Eya1 Phosphatase Mediates Shh-Driven Symmetric Cell Division of Cerebellar Granule Cell PrecursorsDaniel J Merk, Pengcheng Zhou, Samuel M Cohen, et al.Nature Medicine|September 12, 2017
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitorsJulia E Neumann, Annika K Wefers, Sander Lambo, et al.Genome Biology|December 1, 2024
Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumorsDaniel J Merk, Foteini Tsiami, Sophie Hirsch, et al.Developmental Cell|March 20, 2018
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH MedulloblastomaDaniel J Merk, Jasmin Ohli, Natalie D Merk, et al.Neuro-Oncology Advances|March 14, 2023
Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous systemMirjam Renovanz, Sylvia C Kurz, Johannes Rieger, et al.Pageof 15