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Molecular and Cellular Biochemistry|October 6, 1997
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injuryA P Halestrap, C P Connern, E J Griffiths, et al.Biochemistry|June 25, 1996
Chaotropic agents and increased matrix volume enhance binding of mitochondrial cyclophilin to the inner mitochondrial membrane and sensitize the mitochondrial permeability transition to [Ca2+]C P Connern, A P HalestrapThe Biochemical Journal|September 1, 1994
Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channelC P Connern, A P HalestrapThe Biochemical Journal|June 1, 1992
Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilinC P Connern, A P HalestrapThe Journal of Biological Chemistry|February 7, 1997
Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocaseA P Halestrap, K Y Woodfield, C P ConnernThe Biochemical Journal|March 1, 1993
Pyrophosphate metabolism in the perfused heart and isolated heart mitochondria and its role in regulation of mitochondrial function by calciumE J Griffiths, A P HalestrapJournal of Molecular and Cellular Cardiology|December 1, 1993
Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat heartsE J Griffiths, A P HalestrapThe Biochemical Journal|April 1, 1995
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusionE J Griffiths, A P HalestrapThe Biochemical Journal|March 1, 1991
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporinE J Griffiths, A P HalestrapPharmacology & Therapeutics|April 24, 2001
Mitochondria: a target for myocardial protectionM S Suleiman, A P Halestrap, E J GriffithsPageof 13