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Journal of Medicinal Chemistry|February 1, 1982
Lipophilic 5'-(alkyl phosphate) esters of 1-beta-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugsA Rosowsky, S H Kim, J Ross, et al.Biochemical Pharmacology|May 16, 2000
Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithine (PT523) and its B-ring analoguesJ E Wright, C M Vaidya, Y Chen, et al.Journal of Medicinal Chemistry|April 1, 1991
Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chainA Rosowsky, R A Forsch, H Bader, et al.Molecular Pharmacology|April 1, 1994
Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cellsM S Rhee, J Galivan, J E Wright, et al.Journal of Medicinal Chemistry|March 26, 1999
Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritreximA Rosowsky, A T Papoulis, R A Forsch, et al.Journal of Medicinal Chemistry|October 1, 1984
A mechanism for the addition of multiple moles of glutamate by folylpolyglutamate synthetaseR G Moran, P D Colman, R A Forsch, et al.Cancer Research|January 1, 1980
Comparison of pharmacokinetics of 5-fluorouracil and 5-fluorouracil with concurrent thymidine infusions in a Phase I trialJ M Kirkwood, W Ensminger, A Rosowsky, et al.The Journal of Biological Chemistry|December 10, 1982
A new fluorescent dihydrofolate reductase probe for studies of methotrexate resistanceA Rosowsky, J E Wright, H Shapiro, et al.The Journal of Biological Chemistry|September 25, 1989
Wild-type and drug-resistant Leishmania major hydrolyze methotrexate to N-10-methyl-4-deoxy-4-aminopteroate without accumulation of methotrexate polyglutamatesT E Ellenberger, J E Wright, A Rosowsky, et al.Journal of Medicinal Chemistry|December 23, 1994
2,4-Diamino-5-chloroquinazoline analogues of trimetrexate and piritrexim: synthesis and antifolate activityA Rosowsky, C E Mota, J E Wright, et al.Pageof 43