Showing results (51-60 of 422) with videos related to
Sort By:
Pageof 43
Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 34. Replacement of the glutamate moiety in methotrexate and aminopterin by long-chain 2-aminoalkanedioic acidsA Rosowsky, H Bader, W Kohler, et al.Journal of Medicinal Chemistry|July 8, 1994
Synthesis and biological activity of N omega-hemiphthaloyl-alpha,omega- diaminoalkanoic acid analogues of aminopterin and 3',5-dichloroaminopterinA Rosowsky, H Bader, J E Wright, et al.Journal of Medicinal Chemistry|July 1, 1984
Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugatesA Rosowsky, R A Forsch, J H Freisheim, et al.British Journal of Cancer|July 1, 1990
1,2-dithiol-3-thione and dithioester analogues: potential radioprotectorsB A Teicher, J Stemwedel, T S Herman, et al.Cancer Chemotherapy and Pharmacology|January 1, 1995
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivoS A Holden, B A Teicher, M F Robinson, et al.Journal of Medicinal Chemistry|April 1, 1988
Methotrexate analogues. 31. Meta and ortho isomers of aminopterin, compounds with a double bond in the side chain, and a novel analogue modified at the alpha-carbon: chemical and in vitro biological studiesA Rosowsky, H Bader, R A Forsch, et al.Molecular Pharmacology|January 1, 1985
Regiospecific gamma-conjugation of methotrexate to poly(L-lysine). Chemical and biological studiesA Rosowsky, R A Forsch, J Galivan, et al.Journal of Medicinal Chemistry|July 1, 1988
Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibitionA Rosowsky, R A Forsch, R G Moran, et al.Biochemical Pharmacology|January 1, 1984
Methotrexate analogues--XVII. Antitumor activity of 4-amino-4-deoxy-N10-methylpteroyl-D,L-homocysteic acid and its dual inhibition of dihydrofolate reductase and folyl polyglutamate synthetaseA Rosowsky, R G Moran, R Forsch, et al.Journal of Medicinal Chemistry|May 1, 1984
Methotrexate analogues. 19. Replacement of the glutamate side chain in classical antifolates by L-homocysteic acid and L-cysteic acid: effect on enzyme inhibition and antitumor activityA Rosowsky, R A Forsch, J H Freisheim, et al.Pageof 43