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Journal of Medicinal Chemistry|May 1, 1984
Methotrexate analogues. 21. Divergent influence of alkyl chain length on the dihydrofolate reductase affinity and cytotoxicity of methotrexate monoestersA Rosowsky, R A Forsch, C S Yu, et al.Journal of Medicinal Chemistry|January 31, 1997
Analogues of N alpha-(4-amino-4-deoxypteroyl)-N delta-hemiphthaloyl-L-ornithine (PT523) modified in the side chain: synthesis and biological evaluationA Rosowsky, C M Vaidya, H Bader, et al.Antimicrobial Agents and Chemotherapy|December 20, 2000
Efficacies of lipophilic inhibitors of dihydrofolate reductase against parasitic protozoaH Lau, J T Ferlan, V H Brophy, et al.Journal of Medicinal Chemistry|April 26, 2000
Analogues of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L-ornithine (PT523) with modifications in the side chain, p-aminobenzoyl moiety, or 9,10-bridge: synthesis and in vitro antitumor activityA Rosowsky, J E Wright, C M Vaidya, et al.Molecular Pharmacology|January 1, 1985
Structural features of 4-amino antifolates required for substrate activity with mammalian folylpolyglutamate synthetaseR G Moran, P D Colman, A Rosowsky, et al.Journal of Medicinal Chemistry|May 1, 1992
Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: synthesis and in vitro biological evaluationA Rosowsky, R A Forsch, V E Reich, et al.Biochemistry|December 31, 1997
Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523V Cody, N Galitsky, J R Luft, et al.Analytical Biochemistry|January 1, 1995
Analysis of 4-hydroxycyclophosphamide in human bloodJ E Wright, O Tretyakov, L J Ayash, et al.Journal of Medicinal Chemistry|December 2, 1999
Structure-based design of selective inhibitors of dihydrofolate reductase: synthesis and antiparasitic activity of 2, 4-diaminopteridine analogues with a bridged diarylamine side chainA Rosowsky, V Cody, N Galitsky, et al.Journal of Medicinal Chemistry|August 1, 1997
Synthesis and in vitro activity of long-chain 5'-O-[(alkoxycarbonyl)phosphinyl]-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1A Rosowsky, H Fu, N Pai, et al.Pageof 43