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Journal of Medicinal Chemistry|January 5, 2007
Development of dihydropyridone indazole amides as selective Rho-kinase inhibitorsKrista B Goodman, Haifeng Cui, Sarah E Dowdell, et al.Bioorganic & Medicinal Chemistry Letters|June 6, 2008
Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profilesJohn J McAtee, Jason W Dodson, Sarah E Dowdell, et al.Molecular Cell|December 3, 2014
RIP3 induces apoptosis independent of pronecrotic kinase activityPratyusha Mandal, Scott B Berger, Sirika Pillay, et al.Journal of Medicinal Chemistry|February 3, 2017
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory DiseasesPhilip A Harris, Scott B Berger, Jae U Jeong, et al.Journal of Medicinal Chemistry|April 24, 2019
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) KinasePhilip A Harris, Nicolas Faucher, Nicolas George, et al.Pageof 3