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The EMBO Journal|September 1, 2020
The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol traffickingJorge Montesinos, Marta Pera, Delfina Larrea, et al.
Annals of the New York Academy of Sciences|March 31, 2012
The sixth annual translational stem cell research conference of the New York Stem Cell FoundationCaroline Marshall, Haiqing Hua, Linshan Shang, et al.
Plos One|January 14, 2014
Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitorsAndrew A Sproul, Samson Jacob, Deborah Pre, et al.
Nature Communications|January 4, 2019
CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavageJichao Sun, Jared Carlson-Stevermer, Utpal Das, et al.
Cell Death & Disease|November 15, 2022
Genuine selective caspase-2 inhibition with new irreversible small peptidomimeticsElodie Bosc, Julie Anastasie, Feryel Soualmia, et al.
Acta Neuropathologica|June 25, 2024
Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APP<sup>V717I</sup> mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediatorWenhui Qu, Matti Lam, Julie J McInvale, et al.
Brain, Behavior, and Immunity|June 1, 2025
HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptakeVerena Haage, John F Tuddenham, Alex Bautista, et al.
Biorxiv : the Preprint Server for Biology|March 30, 2023
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's diseaseAnne Marie W Bartosch, Elliot H H Youth, Shania Hansen, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|December 5, 2023
ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's DiseaseAnne Marie W Bartosch, Elliot H H Youth, Shania Hansen, et al.
Biorxiv : the Preprint Server for Biology|February 19, 2024
A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's diseaseVerena Haage, John F Tuddenham, Natacha Comandante-Lou, et al.
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