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Bioorganic & Medicinal Chemistry Letters
|
April 2, 2010
Synthesis and structure-activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARalpha selective activators- PPARalpha and PPARgamma selectivity modulation
Xiang-Yang Ye, Stephanie Chen, Hao Zhang, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2008
Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain
Jun Li, Stephanie Y Chen, Shiwei Tao, et al.
ACS Medicinal Chemistry Letters
|
December 18, 2020
Novel Tricyclic Pyroglutamide Derivatives as Potent RORγt Inverse Agonists Identified using a Virtual Screening Approach
Qingjie Liu, Douglas G Batt, Carolyn A Weigelt, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 22, 2017
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors
Lan-Ying Qin, Zheming Ruan, Robert J Cherney, et al.
Journal of Medicinal Chemistry
|
May 10, 1996
Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity
P Chen, P T Cheng, M Alam, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2020
Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists - Exploring C6 and C8 SAR using late-stage functionalization
Qing Shi, Zili Xiao, Michael G Yang, et al.
Journal of Medicinal Chemistry
|
August 18, 2016
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)
George V De Lucca, Qing Shi, Qingjie Liu, et al.
Journal of Medicinal Chemistry
|
November 2, 2007
Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180)
Jun Li, Stephanie Y Chen, James J Li, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 48) with videos related to
Sort By:
Page
of 5
Bioorganic & Medicinal Chemistry Letters
|
April 2, 2010
Synthesis and structure-activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARalpha selective activators- PPARalpha and PPARgamma selectivity modulation
Xiang-Yang Ye, Stephanie Chen, Hao Zhang, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 26, 2008
Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain
Jun Li, Stephanie Y Chen, Shiwei Tao, et al.
ACS Medicinal Chemistry Letters
|
December 18, 2020
Novel Tricyclic Pyroglutamide Derivatives as Potent RORγt Inverse Agonists Identified using a Virtual Screening Approach
Qingjie Liu, Douglas G Batt, Carolyn A Weigelt, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 22, 2017
Discovery of 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives as highly potent and selective PI3Kδ inhibitors
Lan-Ying Qin, Zheming Ruan, Robert J Cherney, et al.
Journal of Medicinal Chemistry
|
May 10, 1996
Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity
P Chen, P T Cheng, M Alam, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2020
Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists - Exploring C6 and C8 SAR using late-stage functionalization
Qing Shi, Zili Xiao, Michael G Yang, et al.
Journal of Medicinal Chemistry
|
August 18, 2016
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)
George V De Lucca, Qing Shi, Qingjie Liu, et al.
Journal of Medicinal Chemistry
|
November 2, 2007
Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180)
Jun Li, Stephanie Y Chen, James J Li, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
Page
of 5