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Journal of Huntington'S Disease|September 4, 2015
Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative PhenotypeMichal Wegrzynowicz, Terry Jo Bichell, Barbara D Soares, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|September 18, 2022
Treatment with THI, an inhibitor of sphingosine-1-phosphate lyase, modulates glycosphingolipid metabolism and results therapeutically effective in experimental models of Huntington's diseaseGiuseppe Pepe, Luca Capocci, Federico Marracino, et al.Scientific Reports|May 26, 2018
Author Correction: Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's diseaseAlba Di Pardo, Enrico Amico, Abdul Basit, et al.Journal of Neuroinflammation|December 14, 2016
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unitJacquelyn A Brown, Simona G Codreanu, Mingjian Shi, et al.Scientific Reports|July 15, 2017
Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's diseaseAlba Di Pardo, Enrico Amico, Abdul Basit, et al.Proceedings of the National Academy of Sciences of the United States of America|October 29, 2015
Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 miceTristano Pancani, Daniel J Foster, Mark S Moehle, et al.Biomicrofluidics|November 18, 2015
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactorJacquelyn A Brown, Virginia Pensabene, Dmitry A Markov, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 30, 2021
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic VariantZhefu Que, Maria I Olivero-Acosta, Jingliang Zhang, et al.Biochimica Et Biophysica Acta. Molecular Basis of Disease|February 19, 2017
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse modelTerry Jo V Bichell, Michal Wegrzynowicz, K Grace Tipps, et al.American Journal of Physiology. Cell Physiology|May 30, 2014
Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertensionJames D West, Eric D Austin, Christa Gaskill, et al.Pageof 17