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The Journal of Organic Chemistry
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May 24, 2018
Solvent-Controlled, Site-Selective N-Alkylation Reactions of Azolo-Fused Ring Heterocycles at N1-, N2-, and N3-Positions, Including Pyrazolo[3,4- d]pyrimidines, Purines, [1,2,3]Triazolo[4,5]pyridines, and Related Deaza-Compounds
Brett C Bookser, Michael I Weinhouse, Aaron C Burns, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
April 11, 2022
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer
Joshua K Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, et al.
Journal of Medicinal Chemistry
|
January 18, 2022
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of <i>MTAP</i>-Deleted Cancers
Christopher R Smith, Ruth Aranda, Thomas P Bobinski, et al.
Journal of Medicinal Chemistry
|
July 14, 2022
Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction
John M Ketcham, Jacob Haling, Shilpi Khare, et al.
Journal of Medicinal Chemistry
|
March 13, 2024
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
John M Ketcham, Stephen J Harwood, Ruth Aranda, et al.
Journal of Medicinal Chemistry
|
April 7, 2020
Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer
Jay B Fell, John P Fischer, Brian R Baer, et al.
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Search research articles
Search
Showing results (11-20 of 16) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 16 results.
The Journal of Organic Chemistry
|
May 24, 2018
Solvent-Controlled, Site-Selective N-Alkylation Reactions of Azolo-Fused Ring Heterocycles at N1-, N2-, and N3-Positions, Including Pyrazolo[3,4- d]pyrimidines, Purines, [1,2,3]Triazolo[4,5]pyridines, and Related Deaza-Compounds
Brett C Bookser, Michael I Weinhouse, Aaron C Burns, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
April 11, 2022
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer
Joshua K Sabari, Vamsidhar Velcheti, Kazuhide Shimizu, et al.
Journal of Medicinal Chemistry
|
January 18, 2022
Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of <i>MTAP</i>-Deleted Cancers
Christopher R Smith, Ruth Aranda, Thomas P Bobinski, et al.
Journal of Medicinal Chemistry
|
July 14, 2022
Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction
John M Ketcham, Jacob Haling, Shilpi Khare, et al.
Journal of Medicinal Chemistry
|
March 13, 2024
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
John M Ketcham, Stephen J Harwood, Ruth Aranda, et al.
Journal of Medicinal Chemistry
|
April 7, 2020
Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer
Jay B Fell, John P Fischer, Brian R Baer, et al.
Page
of 2