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FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|August 4, 2012
Defining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblastsAaron N Snead, Paul A Insel
Bioorganic & Medicinal Chemistry Letters|August 30, 2008
Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolitesAaron N Snead, Motonori Miyakawa, Edwin S Tan, et al.
ACS Chemical Biology|May 29, 2007
Thyronamines inhibit plasma membrane and vesicular monoamine transportAaron N Snead, Magda S Santos, Rebecca P Seal, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 30, 2003
Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein dockingGanesh S Anand, Dennis Law, Jeffrey G Mandell, et al.
Molecular Pharmacology|March 5, 2015
G Protein-Coupled Receptor (GPCR) Expression in Native Cells: "Novel" endoGPCRs as Physiologic Regulators and Therapeutic TargetsPaul A Insel, Andrea Wilderman, Alexander C Zambon, et al.
Journal of Medicinal Chemistry|September 18, 2025
Identification of VVD-214/RO7589831, a Clinical-Stage, Covalent Allosteric Inhibitor of WRN Helicase for the Treatment of MSI-High CancersShota Kikuchi, Jason C Green, Don C Rogness, et al.
Nature|April 24, 2024
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicaseKristen A Baltgalvis, Kelsey N Lamb, Kent T Symons, et al.
Biorxiv : the Preprint Server for Biology|January 7, 2025
Covalent inhibitors of the RAS binding domain of PI3Kα impair tumor growth driven by RAS and HER2Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, et al.
Science (New York, N.Y.)|October 9, 2025
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, et al.
Cancer Discovery|December 19, 2025
A covalent allosteric molecular glue suppresses NRF2-dependent cancer growthNilotpal Roy, Tine Wyseure, I-Chung Lo, et al.
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