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Plos Pathogens|June 7, 2019
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agentsBarbara H Stokes, Euna Yoo, James M Murithi, et al.Cancer Research|May 14, 2009
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formationSung-Hee Chang, Keizo Kanasaki, Vasilena Gocheva, et al.Journal of the American Chemical Society|May 25, 2013
Coupling protein engineering with probe design to inhibit and image matrix metalloproteinases with controlled specificityMontse Morell, Thinh Nguyen Duc, Amanda L Willis, et al.Neoplasia (New York, N.Y.)|November 9, 2013
Acid-mediated tumor proteolysis: contribution of cysteine cathepsinsJennifer M Rothberg, Kate M Bailey, Jonathan W Wojtkowiak, et al.Chemistry & Biology|November 13, 2012
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicityHao Li, Elizabeth L Ponder, Martijn Verdoes, et al.Chemistry & Biology|December 25, 2012
The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipainsSara Christina Stolze, Edgar Deu, Farnusch Kaschani, et al.Nature|February 12, 2016
Structure- and function-based design of Plasmodium-selective proteasome inhibitorsHao Li, Anthony J O'Donoghue, Wouter A van der Linden, et al.Scientific Reports|August 15, 2020
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microgliaMaria A Telpoukhovskaia, Kai Liu, Faten A Sayed, et al.ACS Infectious Diseases|October 15, 2016
Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosisChristian S Lentz, Alvaro A Ordonez, Paulina Kasperkiewicz, et al.Journal of the American Chemical Society|August 13, 2024
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA DisplayTong Lan, Cheng Peng, Xiyuan Yao, et al.Pageof 31