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Bioorganic & Medicinal Chemistry Letters|October 21, 2018
Discovery of 5-(2-chloro-4'-(1H-imidazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPDNagarajan Muthukaman, Sanjay Deshmukh, Shital Tondlekar, et al.
Bioorganic & Medicinal Chemistry Letters|November 21, 2016
Discovery of 2-((2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino[2',3':3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitorNagarajan Muthukaman, Sanjay Deshmukh, Neelam Sarode, et al.
Scientific Reports|May 24, 2022
An inhibitor of RORγ for chronic pulmonary obstructive disease treatmentHarshada Desai, Megha Marathe, Varada Potdar, et al.
Bioorganic & Medicinal Chemistry Letters|April 13, 2017
Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain modelNagarajan Muthukaman, Macchindra Tambe, Mahamadhanif Shaikh, et al.
Bioorganic & Medicinal Chemistry Letters|March 10, 2018
Alleviating CYP and hERG liabilities by structure optimization of dihydrofuran-fused tricyclic benzo[d]imidazole series - Potent, selective and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-2Nagarajan Muthukaman, Sanjay Deshmukh, Macchindra Tambe, et al.
Bioorganic & Medicinal Chemistry Letters|November 5, 2017
Discovery of furan and dihydrofuran-fused tricyclic benzo[d]imidazole derivatives as potent and orally efficacious microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors: Part-1Nagarajan Muthukaman, Macchindra Tambe, Sanjay Deshmukh, et al.
European Journal of Medicinal Chemistry|November 16, 2016
A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivativesSujay Basu, Dinesh A Barawkar, Vidya Ramdas, et al.
European Journal of Medicinal Chemistry|April 18, 2017
Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseasesSujay Basu, Dinesh A Barawkar, Vidya Ramdas, et al.
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