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The Journal of Biological Chemistry|June 18, 2014
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicityOssama Khalaf, Bruno Fauvet, Abid Oueslati, et al.Neurobiology of Disease|May 23, 2020
Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primatesAlexander Maxan, Giacomo Sciacca, Melanie Alpaugh, et al.Scientific Reports|October 13, 2022
Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neuronsRazan Sheta, Maxime Teixeira, Walid Idi, et al.Neurobiology of Disease|May 19, 2020
Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primatesPhilippe Gosset, Alexander Maxan, Melanie Alpaugh, et al.Neurobiology of Disease|December 13, 2023
Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington diseaseStefan Bartl, Yuanyun Xie, Nalini Potluri, et al.Neurobiology of Disease|May 15, 2020
Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's diseaseStefan Bartl, Abid Oueslati, Amber L Southwell, et al.Acta Neuropathologica|May 26, 2016
Human-to-mouse prion-like propagation of mutant huntingtin proteinIksoo Jeon, Francesca Cicchetti, Giulia Cisbani, et al.Science Advances|July 10, 2026
Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneityAnne-Laure Mahul-Mellier, Lukas van den Heuvel, Maxime Teixeira, et al.Molecular Psychiatry|June 10, 2020
Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathologyMarie Rieux, Melanie Alpaugh, Giacomo Sciacca, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 6, 2010
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactionsKaterina E Paleologou, Abid Oueslati, Gideon Shakked, et al.Pageof 5