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Molecular Pharmaceutics|May 26, 2018
Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: An In Depth AnalysisAn Van den Bergh, Sandy Van Hemelryck, Jan Bevernage, et al.Pharmaceutical Research|March 14, 2014
Mechanistic understanding of brain drug disposition to optimize the selection of potential neurotherapeutics in drug discoveryIrena Loryan, Vikash Sinha, Claire Mackie, et al.Molecular Pharmaceutics|December 16, 2014
Molecular properties determining unbound intracellular and extracellular brain exposure of CNS drug candidatesIrena Loryan, Vikash Sinha, Claire Mackie, et al.European Journal of Drug Metabolism and Pharmacokinetics|June 19, 2016
Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro-In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept CompoundHuybrecht T'jollyn, Jan Snoeys, Jan Van Bocxlaer, et al.Journal of Pharmacokinetics and Pharmacodynamics|October 14, 2005
Modelling and simulation in the development and use of anti-cancer agents: an underused tool?Ferdinand Rombout, Leon Aarons, Mats Karlsson, et al.Pharmaceutical Research|July 23, 2014
Physiology-based IVIVE predictions of tramadol from in vitro metabolism dataHuybrecht T'jollyn, Jan Snoeys, Pieter Colin, et al.The AAPS Journal|July 26, 2015
Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 MaturationHuybrecht T'jollyn, Jan Snoeys, An Vermeulen, et al.Clinical Pharmacokinetics|December 14, 2007
Predicting oral clearance in humans: how close can we get with allometry?Vikash K Sinha, Stefan S De Buck, Luca A Fenu, et al.Clinical Pharmacokinetics|April 5, 2011
Towards a better prediction of peak concentration, volume of distribution and half-life after oral drug administration in man, using allometryVikash K Sinha, Karin Vaarties, Stefan S De Buck, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|March 19, 2014
In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effectsErik Sjögren, Bertil Abrahamsson, Patrick Augustijns, et al.Pageof 3