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Organic & Biomolecular Chemistry|October 11, 2016
Intramolecular thermal stepwise [2 + 2] cycloadditions: investigation of a stereoselective synthesis of [n.2.0]-bicyclolactonesAdam Throup, Laurence H Patterson, Helen M SheldrakeBioorganic & Medicinal Chemistry Letters|July 9, 2017
Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazinesSabin Llona-Minguez, Maria Häggblad, Ulf Martens, et al.Structure (London, England : 1993)|February 8, 2018
Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural FoldMegan Carter, Ann-Sofie Jemth, Jordi Carreras-Puigvert, et al.Organic & Biomolecular Chemistry|September 12, 2017
Novel spirocyclic systems via multicomponent aza-Diels-Alder reactionSabin Llona-Minguez, Adam Throup, Emilie Steiner, et al.Cancers|August 26, 2023
Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer TherapyMark Sutherland, Andrew Gordon, Fatemah O F O Al-Shammari, et al.RSC Medicinal Chemistry|September 16, 2024
Sidechain structure-activity relationships of cyclobutane-based small molecule αvβ3 antagonistsAdam Throup, Manar Saleh Zraikat, Andrew Gordon, et al.The Journal of Biological Chemistry|March 23, 2021
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivityDaniel Rehling, Si Min Zhang, Ann-Sofie Jemth, et al.Cell Chemical Biology|June 30, 2021
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovirSi Min Zhang, Daniel Rehling, Ann-Sofie Jemth, et al.Nature Communications|December 6, 2024
Coupling cellular drug-target engagement to downstream pharmacology with CeTEAMNicholas C K Valerie, Kumar Sanjiv, Oliver Mortusewicz, et al.Nature Chemical Biology|July 22, 2020
Development of a chemical probe against NUDT15Si Min Zhang, Matthieu Desroses, Anna Hagenkort, et al.Pageof 1