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Critical Reviews in Microbiology|February 12, 2024
Tumor-targeting bacteria as immune stimulants - the future of cancer immunotherapy?Alexandra M Mowday, Jella M van de Laak, Zhe Fu, et al.ACS Medicinal Chemistry Letters|November 17, 2023
Design and Biological Evaluation of Piperazine-Bearing Nitrobenzamide Hypoxia/GDEPT Prodrugs: The Discovery of CP-506Amir Ashoorzadeh, Alexandra M Mowday, Maria R Abbattista, et al.Journal of Structural Biology|November 3, 2015
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealedYuliana Yosaatmadja, Shevan Silva, James M Dickson, et al.Biochemical Pharmacology|August 19, 2014
Identification of one-electron reductases that activate both the hypoxia prodrug SN30000 and diagnostic probe EF5Jingli Wang, Chris P Guise, Gabi U Dachs, et al.Frontiers in Pharmacology|February 25, 2022
Tissue Pharmacokinetic Properties and Bystander Potential of Hypoxia-Activated Prodrug CP-506 by Agent-Based ModellingVictoria Jackson-Patel, Emily Liu, Matthew R Bull, et al.Biochemical Pharmacology|September 25, 2003
3-substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitroMohammed Jaffar, Roger M Phillips, Kaye J Williams, et al.Chinese Journal of Cancer|July 13, 2013
Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxiaChristopher P Guise, Alexandra M Mowday, Amir Ashoorzadeh, et al.Bioorganic & Medicinal Chemistry Letters|July 8, 2020
Synthesis and antiproliferative activity of C- and N-terminal analogues of culicinin DFreda F Li, Louise A Stubbing, Iman Kavianinia, et al.Cancer Research|April 16, 2009
DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicityRachelle S Singleton, Christopher P Guise, Dianne M Ferry, et al.ACS Medicinal Chemistry Letters|August 16, 2019
Rotational Freedom, Steric Hindrance, and Protein Dynamics Explain BLU554 Selectivity for the Hinge Cysteine of FGFR4Xiaojing Lin, Yuliana Yosaatmadja, Maria Kalyukina, et al.Pageof 9