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Genes & Development|May 27, 2018
Regulation of lipid peroxidation and ferroptosis in diverse speciesMarcus Conrad, Valerian E Kagan, Hülya Bayir, et al.Journal of Medicinal Chemistry|April 25, 2018
Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4Cong Li, Xiaobing Deng, Weilin Zhang, et al.Cancer Research|November 4, 2010
Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivationPankaj Kumar Mandal, Manuela Schneider, Pirkko Kölle, et al.Science Advances|March 20, 2026
Caspase-3/7 deficiency results in enhanced intestinal inflammation and reduced tumorigenesisWei Xie, Laura Wyckaert, Mike Vadi, et al.Neoplasia (New York, N.Y.)|March 18, 2010
Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activityManuela Schneider, Markus Wortmann, Pankaj Kumar Mandal, et al.Nature Communications|May 12, 2018
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferationJonathan Muri, Sebastian Heer, Mai Matsushita, et al.Frontiers in Oncology|May 9, 2022
Glioblastoma Relapses Show Increased Markers of Vulnerability to FerroptosisHelena Kram, Georg Prokop, Bernhard Haller, et al.Scientific Reports|January 19, 2018
The ferroptosis inducer erastin irreversibly inhibits system x<sub>c</sub>- and synergizes with cisplatin to increase cisplatin's cytotoxicity in cancer cellsMami Sato, Ryosuke Kusumi, Shinji Hamashima, et al.VASA. Zeitschrift Fur Gefasskrankheiten|November 14, 2022
Cancer, cancer treatment and aneurysmatic ascending aorta growth within a retrospective single center studyKathrin Kobus, Bianca Bohmann, Manuel Wilbring, et al.Journal of the American Chemical Society|August 3, 2022
Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell DeathLuke A Farmer, Zijun Wu, Jia-Fei Poon, et al.Pageof 21