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Current Alzheimer Research|June 25, 2005
Development of a high throughput drug screening assay for the detection of changes in tau levels -- proof of concept with HSP90 inhibitorsChad A Dickey, Jason Eriksen, Adeela Kamal, et al.Blood|June 24, 2005
ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemiaJanuario E Castro, Carlos E Prada, Olivier Loria, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 9, 2006
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sitesChad A Dickey, Judith Dunmore, Bingwei Lu, et al.Molecular Therapy Oncolytics|December 23, 2021
Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistanceJennifer L Green, Robin E Osterhout, Amy L Klova, et al.Journal of Medicinal Chemistry|November 5, 2016
Structure-Cytotoxicity Relationships of Analogues of N14-Desacetoxytubulysin HDorin Toader, Fengjiang Wang, Lakshmaiah Gingipalli, et al.Journal of Neurochemistry|October 27, 2006
The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitisCinzia Dello Russo, Paul E Polak, Pilar R Mercado, et al.Pigment Cell & Melanoma Research|November 6, 2025
Combination of the Novel RAF Dimer Inhibitor Brimarafenib With the MEK Inhibitor Mirdametinib Is Effective Against NRAS Mutant MelanomaFlavia L Tellenbach, Luzia Seiler, Mark Johnson, et al.Journal of Medicinal Chemistry|July 9, 2004
Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90Jean-Yves Le Brazidec, Adeela Kamal, David Busch, et al.The Journal of Clinical Investigation|February 17, 2007
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteinsChad A Dickey, Adeela Kamal, Karen Lundgren, et al.Molecular Cancer Therapeutics|April 18, 2009
BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90Karen Lundgren, Hong Zhang, John Brekken, et al.Pageof 3