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Current Protocols|October 30, 2024
Optimizing CAR-NK Cell Transduction and Expansion: Leveraging Cytokine Modulation for Enhanced PerformanceTiziano Ingegnere, Benjamin Segain, Adeline Cozzani, et al.Cell Reports|December 28, 2020
CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene LociJonathan Martinez-Fabregas, Luopin Wang, Elizabeth Pohler, et al.Cell Death & Disease|December 5, 2024
Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activitiesLydia Ziane-Chaouche, Antonella Raffo-Romero, Nawale Hajjaji, et al.Science Signaling|September 16, 2020
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand dosesClaire Gorby, Junel Sotolongo Bellón, Stephan Wilmes, et al.Elife|November 28, 2019
Kinetics of cytokine receptor trafficking determine signaling and functional selectivityJonathan Martinez-Fabregas, Stephan Wilmes, Luopin Wang, et al.Current Research in Translational Medicine|January 9, 2022
A potential role of preexisting inflammation in the development of acute myelopathy following CAR T-cell therapy for diffuse large B-cell lymphomaDavid Beauvais, Adeline Cozzani, Anne-Sophie Blaise, et al.Iscience|March 21, 2024
MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myelomaLama Hasan Bou Issa, Léa Fléchon, William Laine, et al.Science Immunology|December 2, 2022
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective muteinSilvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani, et al.Nature|June 6, 2020
A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cellsRabab Nasrallah, Charlotte J Imianowski, Lara Bossini-Castillo, et al.Pageof 1