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British Journal of Pharmacology|July 16, 2013
Pharmacological profiling of the TRPV3 channel in recombinant and native assaysOlivera Grubisha, Adrian J Mogg, Jessica L Sorge, et al.
Cerebral Cortex (New York, N.Y. : 1991)|October 17, 2015
Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the HippocampusSiobhan H Dennis, Francesca Pasqui, Ellen M Colvin, et al.
Molecular Pharmacology|March 28, 2008
Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptorsRuud Zwart, Anna L Carbone, Mirko Moroni, et al.
British Journal of Pharmacology|October 3, 2018
Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptorsLisa M Broad, Helen E Sanger, Adrian J Mogg, et al.
Psychopharmacology|January 17, 2014
Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neuronsJeffrey L Dage, Ellen M Colvin, Antoine Fouillet, et al.
Molecular Pharmacology|April 27, 2018
Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial OutcomesSophie J Bradley, Colin Molloy, Christoffer Bundgaard, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 13, 2018
In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission TomographyAdrian J Mogg, Thomas Eessalu, Megan Johnson, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|January 17, 2015
123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivoGeor Bakker, Wilhelmina A Vingerhoets, Jan-Peter van Wieringen, et al.
The Journal of Clinical Investigation|December 20, 2016
M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory lossSophie J Bradley, Julie-Myrtille Bourgognon, Helen E Sanger, et al.
Nature Chemical Biology|February 22, 2020
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugsSophie J Bradley, Colin Molloy, Paulina Valuskova, et al.
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