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Adrian M Isaacs

Showing results (61-70 of 96) with videos related to

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Elife|March 19, 2021
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in <i>Drosophila</i>Magda L Atilano, Sebastian Grönke, Teresa Niccoli, et al.
G3 (Bethesda, Md.)|March 20, 2016
Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogasterJanani Iyer, Qingyu Wang, Thanh Le, et al.
The EMBO Journal|November 18, 2021
C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradationNausicaa V Licata, Riccardo Cristofani, Sally Salomonsson, et al.
Acta Neuropathologica|January 6, 2018
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanismBart Swinnen, Andre Bento-Abreu, Tania F Gendron, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 12, 2003
A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouseAdrian M Isaacs, Peter L Oliver, Emma L Jones, et al.
Human Molecular Genetics|March 13, 2010
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutationsHazel Urwin, Astrid Authier, Jorgen E Nielsen, et al.
Cell Reports|April 9, 2025
Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1-induced endoplasmic reticulum-associated degradationDunxin Shen, Alec Vincent, Evan Udine, et al.
Acta Neuropathologica|January 4, 2019
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1AThomas G Moens, Teresa Niccoli, Katherine M Wilson, et al.
Acta Neuropathologica|July 3, 2013
Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementiaPietro Fratta, Mark Poulter, Tammaryn Lashley, et al.
Nature Communications|September 22, 2023
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9Björn F Vahsen, Sumedha Nalluru, Georgia R Morgan, et al.
Pageof 10

Showing results (61-70 of 96) with videos related to

Sort By:
Pageof 10
Elife|March 19, 2021
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in <i>Drosophila</i>Magda L Atilano, Sebastian Grönke, Teresa Niccoli, et al.
G3 (Bethesda, Md.)|March 20, 2016
Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogasterJanani Iyer, Qingyu Wang, Thanh Le, et al.
The EMBO Journal|November 18, 2021
C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradationNausicaa V Licata, Riccardo Cristofani, Sally Salomonsson, et al.
Acta Neuropathologica|January 6, 2018
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanismBart Swinnen, Andre Bento-Abreu, Tania F Gendron, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 12, 2003
A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouseAdrian M Isaacs, Peter L Oliver, Emma L Jones, et al.
Human Molecular Genetics|March 13, 2010
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutationsHazel Urwin, Astrid Authier, Jorgen E Nielsen, et al.
Cell Reports|April 9, 2025
Differential neuronal vulnerability to C9orf72 repeat expansion driven by Xbp1-induced endoplasmic reticulum-associated degradationDunxin Shen, Alec Vincent, Evan Udine, et al.
Acta Neuropathologica|January 4, 2019
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1AThomas G Moens, Teresa Niccoli, Katherine M Wilson, et al.
Acta Neuropathologica|July 3, 2013
Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementiaPietro Fratta, Mark Poulter, Tammaryn Lashley, et al.
Nature Communications|September 22, 2023
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9Björn F Vahsen, Sumedha Nalluru, Georgia R Morgan, et al.
Pageof 10