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Proceedings of the National Academy of Sciences of the United States of America|November 19, 2003
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistanceRicha Rawat, Adrian Whitty, Peter J TongeOrganic & Biomolecular Chemistry|September 7, 2017
Progress towards the broad use of non-peptide synthetic macrocycles in drug discoveryAdrian Whitty, Lauren A Viarengo, Mengqi ZhongCell Communication & Adhesion|April 18, 2003
Effect of divalent cations on the affinity and selectivity of alpha4 integrins towards the integrin ligands vascular cell adhesion molecule-1 and mucosal addressin cell adhesion molecule-1: Ca2+ activation of integrin alpha4beta1 confers a distinct ligand specificityEric S Day, Laurelee Osborn, Adrian WhittyBiochemistry|October 24, 2012
Binding efficiency of protein-protein complexesEric S Day, Shaun M Cote, Adrian WhittyProceedings of the National Academy of Sciences of the United States of America|December 1, 2023
MEnTaT: A machine-learning approach for the identification of mutations to increase protein stabilitySamantha N Muellers, Karen N Allen, Adrian WhittyJournal of Medicinal Chemistry|June 13, 2019
Why Some Targets Benefit from beyond Rule of Five DrugsMegan Egbert, Adrian Whitty, György M Keserű, et al.Trends in Pharmacological Sciences|November 6, 2015
Lessons from Hot Spot Analysis for Fragment-Based Drug DiscoveryDavid R Hall, Dima Kozakov, Adrian Whitty, et al.Nature Reviews. Drug Discovery|April 2, 2011
The resurgence of covalent drugsJuswinder Singh, Russell C Petter, Thomas A Baillie, et al.Methods in Molecular Biology (Clifton, N.J.)|June 19, 2016
Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting MethodThomas V Riera, Tim J Wigle, Robert A CopelandCurrent Opinion in Chemical Biology|May 26, 2018
Cryptic binding sites on proteins: definition, detection, and druggabilitySandor Vajda, Dmitri Beglov, Amanda E Wakefield, et al.Pageof 8