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Adrian Whitty

Showing results (11-20 of 64) with videos related to

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Journal of Medicinal Chemistry|July 31, 2025
Macrocycles for Conventionally Druggable Targets: Lessons from Macrocyclic Kinase InhibitorsLauren A Viarengo-Baker, Adrian Whitty
Nature Chemical Biology|October 3, 2006
Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor RetSandra Schlee, Paul Carmillo, Adrian Whitty
Oncotarget|August 25, 2015
Fragments and hot spots in drug discoverySandor Vajda, Adrian Whitty, Dima Kozakov
Proceedings of the National Academy of Sciences of the United States of America|November 19, 2003
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistanceRicha Rawat, Adrian Whitty, Peter J Tonge
Organic & Biomolecular Chemistry|September 7, 2017
Progress towards the broad use of non-peptide synthetic macrocycles in drug discoveryAdrian Whitty, Lauren A Viarengo, Mengqi Zhong
Cell Communication & Adhesion|April 18, 2003
Effect of divalent cations on the affinity and selectivity of alpha4 integrins towards the integrin ligands vascular cell adhesion molecule-1 and mucosal addressin cell adhesion molecule-1: Ca2+ activation of integrin alpha4beta1 confers a distinct ligand specificityEric S Day, Laurelee Osborn, Adrian Whitty
Biochemistry|October 24, 2012
Binding efficiency of protein-protein complexesEric S Day, Shaun M Cote, Adrian Whitty
Proceedings of the National Academy of Sciences of the United States of America|December 1, 2023
MEnTaT: A machine-learning approach for the identification of mutations to increase protein stabilitySamantha N Muellers, Karen N Allen, Adrian Whitty
Journal of Medicinal Chemistry|June 13, 2019
Why Some Targets Benefit from beyond Rule of Five DrugsMegan Egbert, Adrian Whitty, György M Keserű, et al.
Trends in Pharmacological Sciences|November 6, 2015
Lessons from Hot Spot Analysis for Fragment-Based Drug DiscoveryDavid R Hall, Dima Kozakov, Adrian Whitty, et al.
Pageof 7

Showing results (11-20 of 64) with videos related to

Sort By:
Pageof 7
Journal of Medicinal Chemistry|July 31, 2025
Macrocycles for Conventionally Druggable Targets: Lessons from Macrocyclic Kinase InhibitorsLauren A Viarengo-Baker, Adrian Whitty
Nature Chemical Biology|October 3, 2006
Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor RetSandra Schlee, Paul Carmillo, Adrian Whitty
Oncotarget|August 25, 2015
Fragments and hot spots in drug discoverySandor Vajda, Adrian Whitty, Dima Kozakov
Proceedings of the National Academy of Sciences of the United States of America|November 19, 2003
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistanceRicha Rawat, Adrian Whitty, Peter J Tonge
Organic & Biomolecular Chemistry|September 7, 2017
Progress towards the broad use of non-peptide synthetic macrocycles in drug discoveryAdrian Whitty, Lauren A Viarengo, Mengqi Zhong
Cell Communication & Adhesion|April 18, 2003
Effect of divalent cations on the affinity and selectivity of alpha4 integrins towards the integrin ligands vascular cell adhesion molecule-1 and mucosal addressin cell adhesion molecule-1: Ca2+ activation of integrin alpha4beta1 confers a distinct ligand specificityEric S Day, Laurelee Osborn, Adrian Whitty
Biochemistry|October 24, 2012
Binding efficiency of protein-protein complexesEric S Day, Shaun M Cote, Adrian Whitty
Proceedings of the National Academy of Sciences of the United States of America|December 1, 2023
MEnTaT: A machine-learning approach for the identification of mutations to increase protein stabilitySamantha N Muellers, Karen N Allen, Adrian Whitty
Journal of Medicinal Chemistry|June 13, 2019
Why Some Targets Benefit from beyond Rule of Five DrugsMegan Egbert, Adrian Whitty, György M Keserű, et al.
Trends in Pharmacological Sciences|November 6, 2015
Lessons from Hot Spot Analysis for Fragment-Based Drug DiscoveryDavid R Hall, Dima Kozakov, Adrian Whitty, et al.
Pageof 7