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Nature Chemical Biology|May 6, 2008
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motilityNobutaka Kato, Tomoyo Sakata, Ghislain Breton, et al.Journal of Medicinal Chemistry|April 25, 2012
Imidazolopiperazines: lead optimization of the second-generation antimalarial agentsAdvait Nagle, Tao Wu, Kelli Kuhen, et al.Antimicrobial Agents and Chemotherapy|December 25, 2013
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitroAnne-Marie Zeeman, Sandra M van Amsterdam, Case W McNamara, et al.ACS Medicinal Chemistry Letters|August 23, 2014
Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stagesBin Zou, Advait Nagle, Arnab K Chatterjee, et al.Nature Communications|November 26, 2014
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparumAkhil B Vaidya, Joanne M Morrisey, Zhongsheng Zhang, et al.Journal of Medicinal Chemistry|June 8, 2011
Imidazolopiperazines: hit to lead optimization of new antimalarial agentsTao Wu, Advait Nagle, Kelli Kuhen, et al.Science (New York, N.Y.)|November 19, 2011
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discoveryStephan Meister, David M Plouffe, Kelli L Kuhen, et al.Antimicrobial Agents and Chemotherapy|June 11, 2014
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmissionKelli L Kuhen, Arnab K Chatterjee, Matthias Rottmann, et al.Nature|November 29, 2013
Targeting Plasmodium PI(4)K to eliminate malariaCase W McNamara, Marcus Cs Lee, Chek Shik Lim, et al.Journal of Medicinal Chemistry|July 16, 2020
Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of LeishmaniasesAdvait Nagle, Agnes Biggart, Celine Be, et al.Pageof 2