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CNS Drugs
|
August 5, 2018
Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain
John A Hey, Petr Kocis, Jakub Hort, et al.
Clinical Pharmacokinetics
|
February 5, 2025
Clinical Pharmacokinetics of Oral ALZ-801/Valiltramiprosate in a 2-Year Phase 2 Trial of APOE4 Carriers with Early Alzheimer's Disease
John A Hey, Jeremy Y Yu, Susan Abushakra, et al.
Clinical Pharmacokinetics
|
October 25, 2017
Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer's Disease
John A Hey, Jeremy Y Yu, Mark Versavel, et al.
Alzheimer'S & Dementia (New York, N. Y.)
|
December 11, 2020
APOE ε4/ε4 homozygotes with early Alzheimer's disease show accelerated hippocampal atrophy and cortical thinning that correlates with cognitive decline
Susan Abushakra, Anton P Porsteinsson, Marwan Sabbagh, et al.
Alzheimer'S & Dementia (New York, N. Y.)
|
August 15, 2024
APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in <i>APOE</i> ε4/ε4 homozygotes with early Alzheimer's disease: Trial design and baseline characteristics
Susan Abushakra, Anton P Porsteinsson, Marwan Sabbagh, et al.
Drugs
|
June 20, 2024
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease
John A Hey, Susan Abushakra, Kaj Blennow, et al.
Drugs
|
September 28, 2025
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial
Susan Abushakra, Aidan Power, David Watson, et al.
CNS Drugs
|
December 1, 2025
Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials
Susan Abushakra, P Murali Doraiswamy, John A Hey, et al.
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Search research articles
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Showing results (11-20 of 18) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 18 results.
CNS Drugs
|
August 5, 2018
Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain
John A Hey, Petr Kocis, Jakub Hort, et al.
Clinical Pharmacokinetics
|
February 5, 2025
Clinical Pharmacokinetics of Oral ALZ-801/Valiltramiprosate in a 2-Year Phase 2 Trial of APOE4 Carriers with Early Alzheimer's Disease
John A Hey, Jeremy Y Yu, Susan Abushakra, et al.
Clinical Pharmacokinetics
|
October 25, 2017
Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer's Disease
John A Hey, Jeremy Y Yu, Mark Versavel, et al.
Alzheimer'S & Dementia (New York, N. Y.)
|
December 11, 2020
APOE ε4/ε4 homozygotes with early Alzheimer's disease show accelerated hippocampal atrophy and cortical thinning that correlates with cognitive decline
Susan Abushakra, Anton P Porsteinsson, Marwan Sabbagh, et al.
Alzheimer'S & Dementia (New York, N. Y.)
|
August 15, 2024
APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in <i>APOE</i> ε4/ε4 homozygotes with early Alzheimer's disease: Trial design and baseline characteristics
Susan Abushakra, Anton P Porsteinsson, Marwan Sabbagh, et al.
Drugs
|
June 20, 2024
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease
John A Hey, Susan Abushakra, Kaj Blennow, et al.
Drugs
|
September 28, 2025
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial
Susan Abushakra, Aidan Power, David Watson, et al.
CNS Drugs
|
December 1, 2025
Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials
Susan Abushakra, P Murali Doraiswamy, John A Hey, et al.
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of 2