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Cancer Discovery|April 15, 2017
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic ModifiersJacob L Glass, Duane Hassane, Bas J Wouters, et al.The EMBO Journal|March 3, 2018
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1Thaneas Prabakaran, Chiranjeevi Bodda, Christian Krapp, et al.Nature|November 26, 2009
Cancer-associated IDH1 mutations produce 2-hydroxyglutarateLenny Dang, David W White, Stefan Gross, et al.The Journal of Clinical Investigation|January 23, 2018
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibitionAnna Sophia McKenney, Allison N Lau, Amritha Varshini Hanasoge Somasundara, et al.Science Translational Medicine|November 25, 2016
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomasJill Bayliss, Piali Mukherjee, Chao Lu, et al.Biorxiv : the Preprint Server for Biology|April 3, 2026
Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibilityCharles Ng, Tak Shun Fung, Dayi Li, et al.Cell|August 2, 2016
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic CancerIok In Christine Chio, Seyed Mehdi Jafarnejad, Mariano Ponz-Sarvise, et al.Cancer Cell|December 7, 2010
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiationMaria E Figueroa, Omar Abdel-Wahab, Chao Lu, et al.Nature Communications|July 9, 2015
Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patientsMark Sausen, Jillian Phallen, Vilmos Adleff, et al.Nature|June 29, 2018
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutationsAndrew M Intlekofer, Alan H Shih, Bo Wang, et al.Pageof 29