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Drug Safety|August 5, 2025
The Impact of COVID-19 and COVID-19 Vaccination on Detection, Assessment, and Management of Suspected Acute Drug-Induced Liver Injury Occurring during Clinical Trials: Consensus Recommendations from the IQ DILI InitiativeMelissa Palmer, Daniel Seekins, Mark Avigan, et al.Respiratory Research|October 30, 2025
Safety and tolerability of astegolimab, an anti-ST2 monoclonal antibody: a narrative reviewSteven G Kelsen, Marcus Maurer, Michael Waters, et al.The Journal of Allergy and Clinical Immunology|August 30, 2022
Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitisMarcus Maurer, Dorothy S Cheung, Wiebke Theess, et al.Clinical and Translational Science|October 2, 2025
Safety, Pharmacokinetics, and Immunogenicity of Astegolimab, an Anti-ST2 Monoclonal Antibody, in Randomized, Phase I Clinical StudiesWenhui Zhang, Dorothy Cheung, Alice Fong, et al.JCI Insight|December 13, 2016
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitisRyan E Feaver, Banumathi K Cole, Mark J Lawson, et al.Gut|February 2, 2023
Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitisFrank Wagner, John C Mansfield, Annemarie N Lekkerkerker, et al.Chemico-Biological Interactions|December 3, 2015
Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytesYlva Terelius, Robert A Figler, Svetlana Marukian, et al.Transplantation and Cellular Therapy|June 1, 2026
A Phase Ib Study of Efmarodocokin Alfa, an Interleukin-22 Agonist, in Combination with Standard of Care, in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantationShukaib Arslan, Corey Cutler, Amin Alousi, et al.Molecular Genetics and Metabolism|January 8, 2016
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytesKimberly A Chapman, Maria S Collado, Robert A Figler, et al.The Journal of Allergy and Clinical Immunology|April 19, 2021
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trialSteven G Kelsen, Ioana O Agache, Weily Soong, et al.Pageof 3