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Cancer Cell
|
November 26, 2018
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, et al.
Cancer Cell
|
February 13, 2019
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, et al.
Nucleic Acids Research
|
December 2, 2016
Pharos: Collating protein information to shed light on the druggable genome
Dac-Trung Nguyen, Stephen Mathias, Cristian Bologa, et al.
Journal of Medicinal Chemistry
|
June 13, 2022
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis
Kevin J Frankowski, Samarjit Patnaik, Chen Wang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 29, 2014
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells
Lesley A Mathews Griner, Rajarshi Guha, Paul Shinn, et al.
Scientific Reports
|
January 23, 2021
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
Dorjbal Dorjsuren, Richard T Eastman, Kathryn J Wicht, et al.
Journal of Medicinal Chemistry
|
April 6, 2021
Discovery and Optimization of 2<i>H</i>-1λ<sup>2</sup>-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer
Jason M Rohde, Surendra Karavadhi, Rajan Pragani, et al.
Journal of Medicinal Chemistry
|
November 10, 2017
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)
Ganesha Rai, Kyle R Brimacombe, Bryan T Mott, et al.
Nature Genetics
|
June 2, 2025
KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage
Zheqi Li, Guillermo Peluffo, Laura E Stevens, et al.
Nature Reviews. Drug Discovery
|
February 24, 2018
Unexplored therapeutic opportunities in the human genome
Tudor I Oprea, Cristian G Bologa, Søren Brunak, et al.
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of 17
Search research articles
Search
Showing results (151-160 of 167) with videos related to
Sort By:
Page
of 17
Cancer Cell
|
November 26, 2018
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, et al.
Cancer Cell
|
February 13, 2019
KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
Kunihiko Hinohara, Hua-Jun Wu, Sébastien Vigneau, et al.
Nucleic Acids Research
|
December 2, 2016
Pharos: Collating protein information to shed light on the druggable genome
Dac-Trung Nguyen, Stephen Mathias, Cristian Bologa, et al.
Journal of Medicinal Chemistry
|
June 13, 2022
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis
Kevin J Frankowski, Samarjit Patnaik, Chen Wang, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 29, 2014
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells
Lesley A Mathews Griner, Rajarshi Guha, Paul Shinn, et al.
Scientific Reports
|
January 23, 2021
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
Dorjbal Dorjsuren, Richard T Eastman, Kathryn J Wicht, et al.
Journal of Medicinal Chemistry
|
April 6, 2021
Discovery and Optimization of 2<i>H</i>-1λ<sup>2</sup>-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer
Jason M Rohde, Surendra Karavadhi, Rajan Pragani, et al.
Journal of Medicinal Chemistry
|
November 10, 2017
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)
Ganesha Rai, Kyle R Brimacombe, Bryan T Mott, et al.
Nature Genetics
|
June 2, 2025
KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage
Zheqi Li, Guillermo Peluffo, Laura E Stevens, et al.
Nature Reviews. Drug Discovery
|
February 24, 2018
Unexplored therapeutic opportunities in the human genome
Tudor I Oprea, Cristian G Bologa, Søren Brunak, et al.
Page
of 17