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ACS Medicinal Chemistry Letters|June 20, 2020
Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-PyrimidinesMami Sato, Hirokazu Fuchida, Naoya Shindo, et al.British Journal of Pharmacology|July 10, 2024
Inhibition of dynamin-related protein 1-filamin interaction improves systemic glucose metabolismYuri Kato, Kohei Ariyoshi, Yasunobu Nohara, et al.ACS Applied Materials & Interfaces|October 24, 2024
Generation of a Nonbilayer Lipid Nanoenvironment after Epitope Binding Potentiates Neutralizing HIV-1 MPER AntibodySara Insausti, Ander Ramos-Caballero, Brian Wiley, et al.Cell Reports|June 10, 2026
The circadian clock component BMAL1 enhances macrophage inflammation by nuclear translocation of peroxisomal β-oxidation enzyme MFP2Akito Tsuruta, Nodoka Hirao, Megumi Shibata, et al.Science Signaling|November 15, 2018
Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescenceAkiyuki Nishimura, Tsukasa Shimauchi, Tomohiro Tanaka, et al.Biochemical and Biophysical Research Communications|May 17, 2024
Hericenone C attenuates the second phase of formalin-induced nociceptive behavior by suppressing the accumulation of CD11c-positive cells in the paw epidermis via phosphorylated P65Junhao Li, Kengo Hamamura, Yuya Yoshida, et al.Journal of Medicinal Chemistry|October 13, 2022
Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL ProteaseYuya Hirose, Naoya Shindo, Makiko Mori, et al.Proceedings of the National Academy of Sciences of the United States of America|March 18, 2009
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compoundShigeki Kiyonaka, Kenta Kato, Motohiro Nishida, et al.Frontiers in Pharmacology|April 3, 2026
Hericenone C exhibits anti-nociceptive effects through RORα-mediated suppression of TLR4 transcriptionJunhao Li, Kengo Hamamura, Yuya Yoshida, et al.Cell Reports|August 20, 2020
Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane EnvironmentsEdurne Rujas, Sara Insausti, Daniel P Leaman, et al.Pageof 10