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Bioorganic & Medicinal Chemistry Letters|June 17, 2006
Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptorWanlong Jiang, Fabio C Tucci, Caroline W Chen, et al.Bioorganic & Medicinal Chemistry Letters|May 3, 2005
A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated miceJoseph Pontillo, Joseph A Tran, Stacy Markison, et al.Bioorganic & Medicinal Chemistry Letters|September 8, 2007
Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptorWanlong Jiang, Fabio C Tucci, Joe A Tran, et al.The European Journal of Neuroscience|July 20, 2005
Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampusJulie V Selkirk, Lisa M Nottebaum, Alicia M Vana, et al.Bioorganic & Medicinal Chemistry Letters|November 23, 2007
Identification and characterization of pyrrolidine diastereoisomers as potent functional agonists and antagonists of the human melanocortin-4 receptorChen Chen, Wanlong Jiang, Joe A Tran, et al.Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Structure-activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptorJoseph Pontillo, Joseph A Tran, Melissa Arellano, et al.Journal of Medicinal Chemistry|October 29, 2008
Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic painBrian Dyck, Junko Tamiya, Florence Jovic, et al.Bioorganic & Medicinal Chemistry|June 5, 2007
Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activityJoe A Tran, Fabio C Tucci, Wanlong Jiang, et al.Journal of Medicinal Chemistry|October 9, 2007
Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexiaChen Chen, Wanlong Jiang, Fabio Tucci, et al.Bioorganic & Medicinal Chemistry|April 18, 2008
Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonistsChen Chen, Fabio C Tucci, Wanlong Jiang, et al.Pageof 7