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Nucleic Acids Research|March 22, 2006
A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivoFanny Turlure, Goedele Maertens, Shaila Rahman, et al.The Journal of Biological Chemistry|October 30, 2009
Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activitySiobhan Hughes, Victoria Jenkins, Mohd Jamal Dar, et al.Plos Pathogens|March 7, 2009
The SET complex acts as a barrier to autointegration of HIV-1Nan Yan, Peter Cherepanov, Janet E Daigle, et al.Nature|February 2, 2010
Retroviral intasome assembly and inhibition of DNA strand transferStephen Hare, Saumya Shree Gupta, Eugene Valkov, et al.Proceedings of the National Academy of Sciences of the United States of America|November 2, 2005
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75Peter Cherepanov, Andre L B Ambrosio, Shaila Rahman, et al.Plos Pathogens|July 18, 2009
Structural basis for functional tetramerization of lentiviral integraseStephen Hare, Francesca Di Nunzio, Alfred Labeja, et al.Proceedings of the National Academy of Sciences of the United States of America|August 25, 2010
Structure-based modeling of the functional HIV-1 intasome and its inhibitionLavanya Krishnan, Xiang Li, Hema L Naraharisetty, et al.Journal of Virology|November 16, 2004
Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replicationRichard Lu, Ana Limón, Eric Devroe, et al.Plos Pathogens|January 10, 2009
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75Stephen Hare, Ming-Chieh Shun, Saumya Shree Gupta, et al.Nature Structural & Molecular Biology|May 17, 2005
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75Peter Cherepanov, Zhen-Yu J Sun, Shaila Rahman, et al.Pageof 18