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Nature|March 8, 2018
Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysisGiovanna Scapin, Venkata P Dandey, Zhening Zhang, et al.
Bioorganic & Medicinal Chemistry Letters|August 3, 2010
Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitorsDavid B Belanger, Patrick J Curran, Alan Hruza, et al.
Bioorganic & Medicinal Chemistry Letters|January 9, 2010
Discovery of C-imidazole azaheptapyridine FPT inhibitorsHugh Y Zhu, Alan B Cooper, Jagdish Desai, et al.
Bioorganic & Medicinal Chemistry Letters|April 17, 2012
Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivityMatthew E Voss, Matthew P Rainka, Mike Fleming, et al.
Bioorganic & Medicinal Chemistry Letters|March 2, 2012
The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophreniaGinny D Ho, W Michael Seganish, Ana Bercovici, et al.
Bioorganic & Medicinal Chemistry Letters|December 7, 2011
Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophreniaShu-Wei Yang, Jennifer Smotryski, William T McElroy, et al.
Biopolymers|October 17, 2007
Structure-guided discovery of cyclin-dependent kinase inhibitorsThierry O Fischmann, Alan Hruza, José S Duca, et al.
Bioorganic & Medicinal Chemistry Letters|October 2, 2007
Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitorsMichael P Dwyer, Kamil Paruch, Carmen Alvarez, et al.
Molecular Cancer Therapeutics|February 3, 2016
Dissecting Therapeutic Resistance to ERK InhibitionSharda Jha, Erick J Morris, Alan Hruza, et al.
ACS Pharmacology & Translational Science|September 19, 2025
The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation InhibitorsKen Ellsworth, Peter Nizner, Anthony Ogawa, et al.
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