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Bioorganic & Medicinal Chemistry Letters|October 2, 2007
Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2Kamil Paruch, Michael P Dwyer, Carmen Alvarez, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent KinasesKamil Paruch, Michael P Dwyer, Carmen Alvarez, et al.Bioorganic & Medicinal Chemistry Letters|May 12, 2018
Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncologySobhana Babu Boga, Abdul-Basit Alhassan, Alan B Cooper, et al.Bioorganic & Medicinal Chemistry Letters|August 31, 2015
Development of a novel tricyclic class of potent and selective FIXa inhibitorsDongfang Meng, Patrick Andre, Thomas J Bateman, et al.Cancer Discovery|April 26, 2013
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitorsErick J Morris, Sharda Jha, Clifford R Restaino, et al.Journal of Medicinal Chemistry|March 1, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase ActivityJack D Scott, Duane E DeMong, Thomas J Greshock, et al.Acta Crystallographica. Section D, Structural Biology|May 26, 2026
The evolving role of structural biology in pharma: integration of X-ray crystallography, cryo-electron microscopy and beyondJill E Chrencik, Hua Poo Su, Yacob Gomez Llorente, et al.Science (New York, N.Y.)|May 7, 2026
Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitideArtis Klapars, Anna Fryszkowska, Stephanie Galanie, et al.Pageof 3