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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 10, 2006
An epilepsy mutation in the sodium channel SCN1A that decreases channel excitabilityArthur J Barela, Salina P Waddy, Jay G Lickfett, et al.
Experimental Neurology|September 28, 2015
An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behaviorChristopher D Makinson, Karoni Dutt, Frank Lin, et al.
Neuron|February 28, 2017
Regulation of Thalamic and Cortical Network Synchrony by Scn8aChristopher D Makinson, Brian S Tanaka, Jordan M Sorokin, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 11, 2013
Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anestheticsMaria I Lioudyno, Alexandra M Birch, Brian S Tanaka, et al.
Neurobiology of Disease|May 5, 2009
A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutationBin Tang, Karoni Dutt, Ligia Papale, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|March 4, 2021
Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse modelJennifer C Wong, Steven F Grieco, Karoni Dutt, et al.
The Journal of Biological Chemistry|January 27, 2010
Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalitiesMelinda S Martin, Karoni Dutt, Ligia A Papale, et al.
Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics|September 27, 2014
The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsantNichole Coleman, Hai M Nguyen, Zhengyu Cao, et al.
Clinical and Translational Science|December 11, 2024
An overview of drug-induced sodium channel blockade and changes in cardiac conduction: Implications for drug safetyKhuram W Chaudhary, Colleen E Clancy, Pei-Chi Yang, et al.
Epilepsia|June 9, 2016
SCN8A encephalopathy: Research progress and prospectsMiriam H Meisler, Guy Helman, Michael F Hammer, et al.
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