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Journal of Medicinal Chemistry
|
March 22, 2018
4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors
Joanne Philp, Brian G Lawhorn, Alan P Graves, et al.
Journal of Medicinal Chemistry
|
October 26, 2021
Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf
Jaclyn R Patterson, Alan P Graves, Patrick Stoy, et al.
ACS Medicinal Chemistry Letters
|
May 18, 2019
Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor
Douglas W Thomson, Daniel Poeckel, Nico Zinn, et al.
Structure (London, England : 1993)
|
April 13, 2016
Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets
Glenn S Van Aller, Alan P Graves, Patricia A Elkins, et al.
Science Translational Medicine
|
October 18, 2013
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart
Ronald J Vagnozzi, Gregory J Gatto, Lara S Kallander, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 29, 2017
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1
Dean E McNulty, William G Bonnette, Hongwei Qi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 8, 2015
HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer
Chun-Fang Xu, Toby Johnson, Xiaojing Wang, et al.
Molecular Cancer Therapeutics
|
September 26, 2014
A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation
Heidi M Ott, Alan P Graves, Melissa B Pappalardi, et al.
Journal of Medicinal Chemistry
|
September 11, 2015
Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)
Brian G Lawhorn, Joanne Philp, Yongdong Zhao, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 11, 2012
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
Michael T McCabe, Alan P Graves, Gopinath Ganji, et al.
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Search research articles
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Showing results (11-20 of 27) with videos related to
Sort By:
Page
of 3
Journal of Medicinal Chemistry
|
March 22, 2018
4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors
Joanne Philp, Brian G Lawhorn, Alan P Graves, et al.
Journal of Medicinal Chemistry
|
October 26, 2021
Identification of Diarylurea Inhibitors of the Cardiac-Specific Kinase TNNI3K by Designing Selectivity Against VEGFR2, p38α, and B-Raf
Jaclyn R Patterson, Alan P Graves, Patrick Stoy, et al.
ACS Medicinal Chemistry Letters
|
May 18, 2019
Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor
Douglas W Thomson, Daniel Poeckel, Nico Zinn, et al.
Structure (London, England : 1993)
|
April 13, 2016
Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets
Glenn S Van Aller, Alan P Graves, Patricia A Elkins, et al.
Science Translational Medicine
|
October 18, 2013
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart
Ronald J Vagnozzi, Gregory J Gatto, Lara S Kallander, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
September 29, 2017
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1
Dean E McNulty, William G Bonnette, Hongwei Qi, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 8, 2015
HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer
Chun-Fang Xu, Toby Johnson, Xiaojing Wang, et al.
Molecular Cancer Therapeutics
|
September 26, 2014
A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation
Heidi M Ott, Alan P Graves, Melissa B Pappalardi, et al.
Journal of Medicinal Chemistry
|
September 11, 2015
Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)
Brian G Lawhorn, Joanne Philp, Yongdong Zhao, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 11, 2012
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
Michael T McCabe, Alan P Graves, Gopinath Ganji, et al.
Page
of 3