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Bioorganic & Medicinal Chemistry Letters
|
February 3, 2005
Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2
Douglas S Williamson, Martin J Parratt, Justin F Bower, et al.
Plos One
|
May 27, 2014
The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats
Derek M Erion, Amanda Lapworth, Paul A Amor, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 3, 2012
Fatty acid amide hydrolase inhibitors. 3: tetra-substituted azetidine ureas with in vivo activity
Stephen D Roughley, Helen Browne, Alba T Macias, et al.
Journal of Medicinal Chemistry
|
July 25, 2019
Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity
Zoltan Szlávik, Levente Ondi, Márton Csékei, et al.
NPJ Breast Cancer
|
July 3, 2019
LobSig is a multigene predictor of outcome in invasive lobular carcinoma
Amy E McCart Reed, Samir Lal, Jamie R Kutasovic, et al.
Bioorganic & Medicinal Chemistry
|
September 29, 2012
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
Nicholas G M Davies, Helen Browne, Ben Davis, et al.
Journal of Medicinal Chemistry
|
November 19, 2020
Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity
Yousuke Yamada, Hajime Takashima, David Lee Walmsley, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Journal of Medicinal Chemistry
|
July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone
Paul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Journal of Medicinal Chemistry
|
February 16, 2017
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
Paul A Brough, Lisa Baker, Simon Bedford, et al.
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of 4
Search research articles
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Showing results (21-30 of 32) with videos related to
Sort By:
Page
of 4
Bioorganic & Medicinal Chemistry Letters
|
February 3, 2005
Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2
Douglas S Williamson, Martin J Parratt, Justin F Bower, et al.
Plos One
|
May 27, 2014
The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats
Derek M Erion, Amanda Lapworth, Paul A Amor, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 3, 2012
Fatty acid amide hydrolase inhibitors. 3: tetra-substituted azetidine ureas with in vivo activity
Stephen D Roughley, Helen Browne, Alba T Macias, et al.
Journal of Medicinal Chemistry
|
July 25, 2019
Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity
Zoltan Szlávik, Levente Ondi, Márton Csékei, et al.
NPJ Breast Cancer
|
July 3, 2019
LobSig is a multigene predictor of outcome in invasive lobular carcinoma
Amy E McCart Reed, Samir Lal, Jamie R Kutasovic, et al.
Bioorganic & Medicinal Chemistry
|
September 29, 2012
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
Nicholas G M Davies, Helen Browne, Ben Davis, et al.
Journal of Medicinal Chemistry
|
November 19, 2020
Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity
Yousuke Yamada, Hajime Takashima, David Lee Walmsley, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Journal of Medicinal Chemistry
|
July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone
Paul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Journal of Medicinal Chemistry
|
February 16, 2017
Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase
Paul A Brough, Lisa Baker, Simon Bedford, et al.
Page
of 4