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Bioorganic & Medicinal Chemistry
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October 20, 2009
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3
Lisa M Havran, Dan C Chong, Wayne E Childers, et al.
Bioorganic & Medicinal Chemistry
|
November 25, 2010
Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists
Kevin G Liu, Albert J Robichaud, Alexander A Greenfield, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 1, 2010
Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonists
Derek C Cole, Jonathan L Gross, Thomas A Comery, et al.
Journal of Medicinal Chemistry
|
July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> Receptor
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Neuropharmacology
|
September 25, 2020
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA<sub>A</sub> receptor positive allosteric modulator
Alison L Althaus, Michael A Ackley, Gabriel M Belfort, et al.
Bioorganic & Medicinal Chemistry
|
October 20, 2009
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Gavin D Heffernan, Richard D Coghlan, Eric S Manas, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 28, 2004
The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs
Su-Er W Huskey, Brian J Dean, George A Doss, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket
Lee D Jennings, Derek C Cole, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets
Derek C Cole, Joseph R Stock, Rajiv Chopra, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 5, 2009
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors
Pawel Nowak, Derek C Cole, Ann Aulabaugh, et al.
Page
of 6
Search research articles
Search
Showing results (41-50 of 54) with videos related to
Sort By:
Page
of 6
Bioorganic & Medicinal Chemistry
|
October 20, 2009
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3
Lisa M Havran, Dan C Chong, Wayne E Childers, et al.
Bioorganic & Medicinal Chemistry
|
November 25, 2010
Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists
Kevin G Liu, Albert J Robichaud, Alexander A Greenfield, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 1, 2010
Benzimidazole- and indole-substituted 1,3'-bipyrrolidine benzamides as histamine H3 receptor antagonists
Derek C Cole, Jonathan L Gross, Thomas A Comery, et al.
Journal of Medicinal Chemistry
|
July 29, 2017
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)<sub>A</sub> Receptor
Gabriel Martinez Botella, Francesco G Salituro, Boyd L Harrison, et al.
Neuropharmacology
|
September 25, 2020
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA<sub>A</sub> receptor positive allosteric modulator
Alison L Althaus, Michael A Ackley, Gabriel M Belfort, et al.
Bioorganic & Medicinal Chemistry
|
October 20, 2009
Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles
Gavin D Heffernan, Richard D Coghlan, Eric S Manas, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
January 28, 2004
The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs
Su-Er W Huskey, Brian J Dean, George A Doss, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket
Lee D Jennings, Derek C Cole, Joseph R Stock, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets
Derek C Cole, Joseph R Stock, Rajiv Chopra, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 5, 2009
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors
Pawel Nowak, Derek C Cole, Ann Aulabaugh, et al.
Page
of 6