Showing results (21-30 of 86) with videos related to
Sort By:
Pageof 9
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 20, 2009
Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducersAlbert P LiCurrent Protocols in Toxicology|October 10, 2012
In vitro evaluation of metabolic drug-drug interactions: a descriptive and critical commentaryAlbert P LiDrug Metabolism and Disposition: the Biological Fate of Chemicals|July 9, 2020
In Vitro Human Cell-Based Experimental Models for the Evaluation of Enteric Metabolism and Drug Interaction Potential of Drugs and Natural ProductsAlbert P LiToxicological Research|July 21, 2015
Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC(TM)) SystemAlbert P LiChemico-Biological Interactions|December 17, 2008
Overview: Evaluation of metabolism-based drug toxicity in drug developmentAlbert P LiChemico-Biological Interactions|October 28, 2008
Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1Albert P LiJournal of Chemical Information and Modeling|October 11, 2011
Applying medicinal chemistry transformations and multiparameter optimization to guide the search for high-quality leads and candidatesMatthew Segall, Ed Champness, Chris Leeding, et al.Drug Metabolism Letters|July 5, 2011
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4Albert P Li, Utkarsh DoshiDrug Metabolism and Disposition: the Biological Fate of Chemicals|November 9, 2021
Permeabilized Cryopreserved Human Hepatocytes as an Exogenous Metabolic System in a Novel Metabolism-Dependent Cytotoxicity Assay for the Evaluation of Metabolic Activation and Detoxification of Drugs Associated with Drug-Induced Liver Injuries: Results with Acetaminophen, Amiodarone, Cyclophosphamide, Ketoconazole, Nefazodone, and TroglitazoneHong Wei, Albert P LiPageof 9