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Journal of Biomolecular Screening|August 12, 2011
Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and inductionUtkarsh Doshi, Albert P LiDrug Metabolism and Disposition: the Biological Fate of Chemicals|June 17, 2021
Messenger RNA Expression of Albumin, Transferrin, Transthyretin, Asialoglycoprotein Receptor, Cytochrome P450 Isoform, Uptake Transporter, and Efflux Transporter Genes as a Function of Culture Duration in Prolonged Cultured Cryopreserved Human Hepatocytes as Collagen-Matrigel Sandwich Cultures: Evidence for Redifferentiation upon Prolonged CulturingQian Yang, Albert P LiMethods in Molecular Biology (Clifton, N.J.)|August 15, 2015
Cryopreservation of HepatocytesNicola J Hewitt, Albert P LiDrug Metabolism Letters|June 10, 2014
Application of a higher throughput approach to derive apparent Michaelis-Menten constants of isoform-selective p450-mediated biotransformation reactions in human hepatocytesAlbert P Li, Kari E SchlichtJournal of Chemical Information and Modeling|May 2, 2020
Predicting pKa Using a Combination of Semi-Empirical Quantum Mechanics and Radial Basis Function MethodsPeter Hunt, Layla Hosseini-Gerami, Tomas Chrien, et al.The Journal of Physical Chemistry. A|November 21, 2007
Theoretical investigations of oxygen-17 NMR chemical shifts to discriminate among helical formsItzam De Gortari, Marcelo Galván, Joel Ireta, et al.Chemico-Biological Interactions|November 4, 2004
A novel in vitro system, the integrated discrete multiple organ cell culture (IdMOC) system, for the evaluation of human drug toxicity: comparative cytotoxicity of tamoxifen towards normal human cells from five major organs and MCF-7 adenocarcinoma breast cancer cellsAlbert P Li, Chris Bode, Yumiko SakaiChemico-Biological Interactions|January 1, 2016
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuriesDoshi Utkarsh, Carol Loretz, Albert P LiChemico-Biological Interactions|May 30, 2012
Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifenAlbert P Li, Aarti Uzgare, Yumiko S LaForgeCurrent Drug Metabolism|April 6, 2012
Effects of culture duration on gene expression of P450 isoforms, uptake and efflux transporters in primary hepatocytes cultured in the absence and presence of interleukin-6: implications for experimental design for the evaluation of downregulatory effects of biotherapeuticsQian Yang, Utkarsh Doshi, Nicole Li, et al.Pageof 9